Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   JM964_RS06280 Genome accession   NZ_CP068708
Coordinates   1291695..1292357 (-) Length   220 a.a.
NCBI ID   WP_202847477.1    Uniprot ID   -
Organism   Streptococcus suis strain ID33329     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1286695..1297357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM964_RS06265 (JM964_06265) sodA 1287629..1288234 (-) 606 WP_013730459.1 superoxide dismutase SodA -
  JM964_RS06270 (JM964_06270) holA 1288347..1289378 (-) 1032 WP_202847475.1 DNA polymerase III subunit delta -
  JM964_RS06275 (JM964_06275) comEC/celB 1289474..1291711 (-) 2238 WP_202847476.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  JM964_RS06280 (JM964_06280) comEA/celA/cilE 1291695..1292357 (-) 663 WP_202847477.1 helix-hairpin-helix domain-containing protein Machinery gene
  JM964_RS06285 (JM964_06285) - 1292425..1293171 (-) 747 WP_014735985.1 lysophospholipid acyltransferase family protein -
  JM964_RS06290 (JM964_06290) - 1293317..1294762 (+) 1446 WP_044674357.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  JM964_RS06295 (JM964_06295) - 1295062..1295847 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  JM964_RS06300 (JM964_06300) - 1295860..1296789 (+) 930 WP_044674354.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23314.10 Da        Isoelectric Point: 4.1214

>NTDB_id=460896 JM964_RS06280 WP_202847477.1 1291695..1292357(-) (comEA/celA/cilE) [Streptococcus suis strain ID33329]
MDTIKTYIEMLKGYKWQIALPAAAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTLSSPEQLEEVSTEASEELSQLVIDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVIYVASKGENISVVASTTASSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=460896 JM964_RS06280 WP_202847477.1 1291695..1292357(-) (comEA/celA/cilE) [Streptococcus suis strain ID33329]
ATGGATACGATTAAAACCTATATAGAAATGCTTAAAGGATACAAGTGGCAGATTGCCTTGCCCGCAGCAGCTGGCTTGCT
TATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACAGGTCTGACAGATTTTCCGCAGACTGAACAAA
CTTTGAGCAGTCCGGAGCAGCTTGAAGAAGTCAGTACAGAAGCAAGTGAGGAGCTTAGTCAGCTAGTCATTGATGTCAAA
GGAGCGGTGGAAAAACCAGGACTTTACACCTTAGAAGCTGGTGCGCGTGTCAATGATGCTGTTGAGGCGGCTGGTGGCTT
GACTAGTCAGGCAGATCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGATCTATGTGGCTAGCAAGG
GCGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCCCAAGAAGAAAAGAACACCAGTCTAGTCAAT
CTCAATACGGCGACCGAGGCGGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAATGGCGGCTTCAAATCGGTGGACGACCTTAACAATGTTTCAGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

45.815

100

0.473
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.032

99.545

0.468
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae D39

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus pneumoniae R6

46.575

99.545

0.464
  comEA/celA/cilE Streptococcus mitis SK321

44.843

100

0.455
  comEA Streptococcus thermophilus LMD-9

58.642

73.636

0.432
  comEA Lactococcus lactis subsp. cremoris KW2

38.71

98.636

0.382
  comEA Bacillus subtilis subsp. subtilis str. 168

39.336

95.909

0.377