Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   I6J12_RS00045 Genome accession   NZ_CP068060
Coordinates   4221..4658 (+) Length   145 a.a.
NCBI ID   WP_003035329.1    Uniprot ID   F9P803
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1..9658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS00010 (I6J12_00010) - 845..1387 (+) 543 WP_003038192.1 DUF1366 domain-containing protein -
  I6J12_RS00015 (I6J12_00015) - 1405..1806 (+) 402 WP_003038210.1 hypothetical protein -
  I6J12_RS00020 (I6J12_00020) - 1808..2140 (+) 333 WP_003038184.1 phage holin -
  I6J12_RS00025 (I6J12_00025) - 2143..2892 (+) 750 WP_003038204.1 PlySs2 family phage lysin -
  I6J12_RS00030 (I6J12_00030) comGC 3315..3584 (+) 270 WP_003035361.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J12_RS00035 (I6J12_00035) comGD 3544..3972 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J12_RS00040 (I6J12_00040) comGE/cglE 3944..4237 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J12_RS00045 (I6J12_00045) comGF/cglF 4221..4658 (+) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J12_RS00050 (I6J12_00050) comGG/cglG 4639..4965 (+) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6J12_RS00055 (I6J12_00055) comGH 5050..6003 (+) 954 WP_003035359.1 class I SAM-dependent methyltransferase Machinery gene
  I6J12_RS00060 (I6J12_00060) - 6050..7249 (+) 1200 WP_003035323.1 acetate kinase -
  I6J12_RS00065 (I6J12_00065) glmS 7639..9453 (+) 1815 WP_020999448.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -

Sequence

Protein


Download         Length: 145 a.a.        Molecular weight: 16865.57 Da        Isoelectric Point: 10.6422

>NTDB_id=458746 I6J12_RS00045 WP_003035329.1 4221..4658(+) (comGF/cglF) [Streptococcus anginosus strain FDAARGOS_1155]
MFKANKVKAFTLLEALVALFVISGSVLLFQSMTRLLASEVRARQHSEQREWLLFAHQLEAELIRSSFEKVENNRLYMKQD
GKTIAFGKSSGQDFRKTNANGKGYQPMIYNVKKAEISQKNELIHIRMTFKRGLEREFVYRVETKS

Nucleotide


Download         Length: 438 bp        

>NTDB_id=458746 I6J12_RS00045 WP_003035329.1 4221..4658(+) (comGF/cglF) [Streptococcus anginosus strain FDAARGOS_1155]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACACTTTTAGAGGCTCTGGTTGCCCTCTTTGTAATCAGCGGGAGTGTGCT
ATTATTTCAATCTATGACGCGTCTTCTGGCTTCGGAGGTCCGAGCTCGACAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCCCATCAATTAGAAGCGGAATTGATTCGTTCTTCATTTGAAAAAGTGGAGAATAATCGTTTATACATGAAGCAGGAC
GGTAAGACGATTGCATTTGGAAAGTCAAGTGGACAAGATTTCAGAAAAACCAATGCAAATGGGAAAGGCTATCAGCCTAT
GATTTATAATGTGAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATATCAGAATGACATTTAAGCGAGGATTGG
AAAGGGAGTTCGTCTATCGTGTGGAAACAAAGAGTTAA

Domains

Predicted by InterProScan.

Putative Competence protein ComGF (ComGF)

(39-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P803

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae R6

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae TIGR4

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae Rx1

66.429

96.552

0.641
  comGF/cglF Streptococcus pneumoniae D39

66.429

96.552

0.641
  comGF/cglF Streptococcus mitis NCTC 12261

65.714

96.552

0.634
  comGF/cglF Streptococcus mitis SK321

65.714

96.552

0.634
  comGF Streptococcus mutans UA159

43.972

97.241

0.428
  comGF Streptococcus mutans UA140

43.972

97.241

0.428
  comGF Lactococcus lactis subsp. cremoris KW2

42.963

93.103

0.4