NTDB

Overview

Name	comE/blpR	Type	Regulator
Locus tag	I6J14_RS09120	Genome accession	NZ_CP068057
Coordinates	1815350..1816090 (+)	Length	246 a.a.
NCBI ID	WP_115253146.1	Uniprot ID	-
Organism	Streptococcus dysgalactiae strain FDAARGOS_1157
Function	activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1810350..1821090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J14_RS09105 (I6J14_09105)	gltX	1810658..1812106 (+)	1449	WP_003052902.1	glutamate--tRNA ligase	-
I6J14_RS09110 (I6J14_09110)	-	1812719..1814062 (+)	1344	WP_115253147.1	GHKL domain-containing protein	-
I6J14_RS09115 (I6J14_09115)	-	1814063..1815346 (+)	1284	WP_003052898.1	sensor histidine kinase	-
I6J14_RS09120 (I6J14_09120)	comE/blpR	1815350..1816090 (+)	741	WP_115253146.1	LytTR family DNA-binding domain-containing protein	Regulator
I6J14_RS09125 (I6J14_09125)	rnpA	1816630..1816989 (+)	360	WP_003052894.1	ribonuclease P protein component	-
I6J14_RS09130 (I6J14_09130)	-	1816955..1817782 (+)	828	WP_115253145.1	YidC/Oxa1 family membrane protein insertase	-
I6J14_RS09135 (I6J14_09135)	jag	1817794..1818708 (+)	915	WP_115276470.1	RNA-binding cell elongation regulator Jag/EloR	-
I6J14_RS09140 (I6J14_09140)	rpmH	1819022..1819156 (+)	135	WP_002885866.1	50S ribosomal protein L34	-
I6J14_RS09145 (I6J14_09145)	-	1819487..1820191 (+)	705	WP_003052885.1	N-acetylmannosamine-6-phosphate 2-epimerase	-

Sequence

Protein

Download Length: 246 a.a. Molecular weight: 28934.26 Da Isoelectric Point: 4.8691

                                >NTDB_id=458721 I6J14_RS09120 WP_115253146.1 1815350..1816090(+) (comE/blpR) [Streptococcus dysgalactiae strain FDAARGOS_1157]

MMNIFILEDDFIQQTRIESVVADILEEAKLPCNQLEVFANPHKLFESIQERGDHQLYFLDIEIGDEARRGLELAADIRQK

DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKEQFRDQIEECIRYTYEMMSSRESEDMFLFETPQTRLKLPYKDIL

YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQLLYFDNGDSCMVSRLKMKCLFE

KWEALH

Nucleotide

Download Length: 741 bp

                                >NTDB_id=458721 I6J14_RS09120 WP_115253146.1 1815350..1816090(+) (comE/blpR) [Streptococcus dysgalactiae strain FDAARGOS_1157]

ATGATGAATATTTTTATTCTTGAAGATGATTTTATTCAACAGACACGTATTGAATCTGTAGTGGCAGACATTTTGGAAGA

GGCTAAATTACCTTGTAATCAGCTAGAAGTGTTTGCCAATCCTCATAAATTATTTGAAAGCATTCAAGAAAGAGGCGACC

ATCAGTTATATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGAGGACTTGAATTGGCAGCAGATATTCGACAAAAA

GACCCCAATGCAGTCATTGTGTTTGTTACCACACATTCTGAATTTGCTCCTATTTCTTTTAAATACAAAGTGTCTGCCTT

AGATTTTATTGACAAAGCAGTTGATAAAGAACAATTTAGGGATCAGATTGAAGAATGTATCCGCTATACCTATGAGATGA

TGTCTAGCCGTGAATCAGAAGATATGTTTTTATTTGAGACCCCTCAGACAAGATTGAAATTACCTTACAAAGATATCCTT

TATTTTGCCACTGCTACGACACCCCATAAGGTGTGTTTGTGGACTCAGACGGAGAGATTGGAGTTTTATGGCAATTTATC

TGAGATACAAGCCGTGGCTCCAAAACTTTTCTTATGTCATAGATCTTACTTGGTTAATCTAGATAAGGTTGTGCGTATTG

ATAAATCCAAACAGCTCCTCTATTTTGATAATGGAGATTCCTGCATGGTCTCACGCTTAAAAATGAAATGCCTTTTTGAA

AAATGGGAGGCCTTACATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.857	96.748	0.415
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	39.516	100	0.398
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.516	100	0.398

Detailed information NTG0458721