Detailed information NTG0458696

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: I6J14_RS07505
• Genome accession: NZ_CP068057
• Coordinates: 1504132..1504572 (-)
• Length: 146 a.a.
• NCBI ID: WP_003049266.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1157
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1499132..1509572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J14_RS10950	-	1499777..1500214 (-)	438	WP_003049278.1	hypothetical protein	-
I6J14_RS07480 (I6J14_07480)	-	1500232..1500837 (-)	606	WP_236593264.1	CPBP family intramembrane glutamic endopeptidase	-
I6J14_RS07485 (I6J14_07485)	-	1500993..1501199 (-)	207	WP_003049274.1	helix-turn-helix transcriptional regulator	-
I6J14_RS07490 (I6J14_07490)	-	1501509..1502705 (-)	1197	WP_003049273.1	acetate kinase	-
I6J14_RS07495 (I6J14_07495)	comGH	1502764..1503717 (-)	954	WP_115246884.1	class I SAM-dependent methyltransferase	Machinery gene
I6J14_RS07500 (I6J14_07500)	comGG	1503780..1504103 (-)	324	WP_236593265.1	competence type IV pilus minor pilin ComGG	-
I6J14_RS07505 (I6J14_07505)	comGF	1504132..1504572 (-)	441	WP_003049266.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6J14_RS07510 (I6J14_07510)	comGE	1504553..1504849 (-)	297	WP_003061797.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6J14_RS07515 (I6J14_07515)	comGD	1504806..1505234 (-)	429	WP_115252504.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6J14_RS07520 (I6J14_07520)	comGC	1505209..1505535 (-)	327	WP_115246891.1	competence type IV pilus major pilin ComGC	Machinery gene
I6J14_RS07525 (I6J14_07525)	comGB	1505537..1506568 (-)	1032	WP_003049254.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6J14_RS07530 (I6J14_07530)	comGA	1506504..1507445 (-)	942	WP_003049251.1	competence type IV pilus ATPase ComGA	Machinery gene
I6J14_RS07535 (I6J14_07535)	-	1507525..1507890 (-)	366	WP_003049248.1	DUF1033 family protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 17006.57 Da
• Isoelectric Point: 10.5665

>NTDB_id=458696 I6J14_RS07505 WP_003049266.1 1504132..1504572(-) (comGF) [Streptococcus dysgalactiae strain FDAARGOS_1157]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTNHDQDHWLLFSQQLREELSGVRFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=458696 I6J14_RS07505 WP_003049266.1 1504132..1504572(-) (comGF) [Streptococcus dysgalactiae strain FDAARGOS_1157]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTGATTGCCTTGCTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGGTTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAACCATGATCAAGACCATTGGCTTT
TATTCTCCCAGCAGCTACGAGAAGAGTTAAGTGGAGTGCGATTTCACAAAGTAGAAAACAATAAATTATATATTGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGTCTGTCTCATAGTCATATACAAGCAGAACAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.482	95.205	0.452
comGF	Streptococcus mutans UA140	46.763	95.205	0.445
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411