Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   JJN14_RS00220 Genome accession   NZ_CP067992
Coordinates   40411..42564 (+) Length   717 a.a.
NCBI ID   WP_201058596.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 35411..47564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS00200 (JJN14_00200) - 35761..36063 (+) 303 WP_236253695.1 hypothetical protein -
  JJN14_RS00205 (JJN14_00205) - 36102..37385 (+) 1284 WP_201058594.1 accessory Sec system glycosyltransferase GtfB -
  JJN14_RS00210 (JJN14_00210) - 37382..38863 (+) 1482 WP_201058595.1 glycosyltransferase -
  JJN14_RS00215 (JJN14_00215) - 38948..39505 (-) 558 Protein_36 transposase -
  JJN14_RS10005 - 40060..40248 (+) 189 WP_236253696.1 hypothetical protein -
  JJN14_RS00220 (JJN14_00220) comA 40411..42564 (+) 2154 WP_201058596.1 peptide cleavage/export ABC transporter ComA Regulator
  JJN14_RS00225 (JJN14_00225) comB 42577..43926 (+) 1350 WP_201058597.1 competence pheromone export protein ComB Regulator
  JJN14_RS00230 (JJN14_00230) purC 44096..44803 (+) 708 WP_201058598.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80168.13 Da        Isoelectric Point: 6.4561

>NTDB_id=458180 JJN14_RS00220 WP_201058596.1 40411..42564(+) (comA) [Streptococcus mitis strain S022-V7-A3]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
AFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLSRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFDEKKTVEDLSLM
KGDMTFKQVHYKYGYGRDVLSDINLTIPKGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILDNLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLSIAERTEKVVVLDQGKIVEEGNHADLLAQGGFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=458180 JJN14_RS00220 WP_201058596.1 40411..42564(+) (comA) [Streptococcus mitis strain S022-V7-A3]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTCTTTGGCTCACTTGCGAGAATTGGCCAAGACAACCATGGATGGGACAACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAAATTGGTTTTGAGACGCGAGCAATTAAGGCGGATATGACGCTCTTTGACTTGCCAGATTTG
GCTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGATCCGGATCCTGGGGTGAAATTGACCAAACTGTCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCTAATATCGTTTTGGCAACACTCTTGGTAACCTTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTTGGGATTATTTCTATTGGGCTGGTTA
TCGTCTATATTCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCTTGTCTATTGAT
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTGCCTATGTCCTTTTTTGCGACACGTCGTACAGGGGAAATCGTGTC
TCGTTTCACGGATGCTAACAGTATCATTGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTATCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTCCCTATCTACACAGTG
ATTATCTTTGCCTTCATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAATGGTATTGAAACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTGCTCAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACTAATCCTTTGGAGAATATCATCAACCTGCAAACTAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAGGTTTATCTGGTAGCTTCTGAGTTTGATGAGAAGAAAACAGTTGAGGATCTGAGCTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGATGTCTTGTCAGATATCAATTTGACTAT
TCCCAAAGGCTCTAAGGTGGCTTTTGTGGGGATTTCGGGGTCAGGTAAGACGACCTTAGCTAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTGCGCCAGTATATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAATGGAACGATTTTGGACAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGATATCGAGCGTATGCCCCTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGAATTTCAGGTGGTCAACGTCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATTTTGGATGAGGCGACCAGCAGTTTGGATATTTTGACAGAGAAGCGAATTGTAGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGCTTGAGCATTGCTGAGCGGACAGAGAAGGTGGTTGTTTTGGATCAGGGCA
AGATTGTTGAAGAAGGAAATCATGCTGATTTACTTGCACAGGGTGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterProScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

98.884

100

0.989
  comA Streptococcus pneumoniae Rx1

98.187

100

0.982
  comA Streptococcus pneumoniae D39

98.187

100

0.982
  comA Streptococcus pneumoniae R6

98.187

100

0.982
  comA Streptococcus mitis SK321

98.047

100

0.98
  comA Streptococcus pneumoniae TIGR4

97.768

100

0.978
  comA Streptococcus gordonii str. Challis substr. CH1

80.614

100

0.806
  comA/nlmT Streptococcus mutans UA159

65.551

100

0.656