Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HV560_RS06645 Genome accession   NZ_CP055305
Coordinates   1373077..1374270 (+) Length   397 a.a.
NCBI ID   WP_176812460.1    Uniprot ID   -
Organism   Mannheimia pernigra strain 17CN0883     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1368077..1379270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HV560_RS06620 (HV560_06620) - 1368768..1369262 (+) 495 WP_159629590.1 dihydrofolate reductase -
  HV560_RS06625 (HV560_06625) - 1369390..1369623 (+) 234 WP_159629593.1 YgjV family protein -
  HV560_RS06630 (HV560_06630) radA 1369662..1371041 (-) 1380 WP_176812457.1 DNA repair protein RadA Machinery gene
  HV560_RS06635 (HV560_06635) pilA 1371222..1371671 (+) 450 WP_176812458.1 prepilin peptidase-dependent pilin Machinery gene
  HV560_RS06640 (HV560_06640) pilB 1371693..1373093 (+) 1401 WP_176812459.1 GspE/PulE family protein Machinery gene
  HV560_RS06645 (HV560_06645) pilC 1373077..1374270 (+) 1194 WP_176812460.1 type II secretion system F family protein Machinery gene
  HV560_RS06650 (HV560_06650) - 1374273..1374929 (+) 657 WP_176812461.1 prepilin peptidase -
  HV560_RS06655 (HV560_06655) coaE 1374961..1375599 (+) 639 WP_176812462.1 dephospho-CoA kinase -
  HV560_RS06660 (HV560_06660) yacG 1375581..1375766 (+) 186 WP_159629615.1 DNA gyrase inhibitor YacG -
  HV560_RS06665 (HV560_06665) holA 1375767..1376789 (-) 1023 WP_176812463.1 DNA polymerase III subunit delta -
  HV560_RS06670 (HV560_06670) lptE 1376830..1377318 (-) 489 WP_176812464.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 397 a.a.        Molecular weight: 45530.13 Da        Isoelectric Point: 9.4575

>NTDB_id=457508 HV560_RS06645 WP_176812460.1 1373077..1374270(+) (pilC) [Mannheimia pernigra strain 17CN0883]
MAKIYEYHWKAVDRFQQKRKGSRLSSSREELESMLLMKGYEQIRINRNFVLSQNPKREQISQFISQLALLVNSAISLKQA
LSMILQNCRNIKMYQWLSELILLIENGYSFSQSLEKQDKFIANQELQLIKMGEQSGKLGIILTNLAKSRAKSDKLAKKVK
KILFYPAIVLFISLSLSLGLLIFIVPQFAELYGTKEKALPLITEILFSLSQCLIEQKHLLLSLLLAVVFFLFFAKRENGF
VRLKMALLSKLPVFRQIIQQARIVFFSQNMALMLNAHIPLDLVLKSFLSEKSDDPILQKEVEFMLNLLQQGYPFSQGINP
NVFGLDMPQMIEIGEQSGNVANICEHISEMYQQKLDYQIDMLSQLLEPMLMLLMGIIVGTIIVGLYLPIFDMGSLVE

Nucleotide


Download         Length: 1194 bp        

>NTDB_id=457508 HV560_RS06645 WP_176812460.1 1373077..1374270(+) (pilC) [Mannheimia pernigra strain 17CN0883]
ATGGCGAAAATCTATGAATACCATTGGAAAGCGGTTGATCGTTTCCAACAAAAACGTAAAGGCAGCCGATTATCTAGCAG
CCGAGAAGAGCTTGAAAGTATGTTGCTAATGAAAGGTTATGAGCAGATTCGCATTAATCGAAACTTCGTTTTATCTCAAA
ATCCGAAAAGAGAGCAGATCAGCCAATTTATTTCCCAGCTTGCGTTATTAGTGAATTCCGCTATATCGTTAAAACAGGCT
CTTTCGATGATTTTACAAAACTGCCGAAATATTAAAATGTATCAATGGCTAAGCGAGCTCATTTTGCTGATTGAAAATGG
TTATTCTTTTTCACAATCATTAGAGAAACAAGATAAATTTATTGCTAATCAAGAACTTCAACTGATTAAAATGGGCGAGC
AAAGCGGAAAACTAGGTATCATCTTAACGAATTTGGCGAAAAGCCGAGCTAAGTCTGATAAGTTAGCTAAAAAAGTGAAG
AAAATCCTGTTTTATCCTGCGATTGTATTGTTTATTTCCCTGTCTCTTTCTCTCGGATTGTTGATCTTCATTGTGCCCCA
GTTTGCAGAACTTTACGGCACAAAAGAGAAAGCCTTACCACTGATTACGGAAATACTATTTTCTCTTTCCCAGTGTTTGA
TTGAACAGAAGCATCTTCTACTTAGTTTATTACTAGCGGTCGTTTTTTTCCTCTTTTTTGCAAAAAGAGAGAACGGGTTT
GTGAGGTTAAAAATGGCGTTATTGTCTAAACTCCCTGTATTTCGACAAATCATACAGCAAGCCCGTATTGTCTTTTTTAG
CCAAAATATGGCTTTAATGTTGAATGCTCATATTCCGTTAGATTTGGTATTAAAATCCTTTTTATCTGAAAAAAGTGATG
ATCCTATATTACAAAAAGAGGTTGAATTTATGCTAAATCTCTTGCAACAAGGCTACCCATTTTCGCAAGGCATTAATCCA
AATGTGTTTGGCTTAGATATGCCACAAATGATCGAAATCGGCGAGCAAAGCGGCAACGTTGCCAACATATGCGAACATAT
TAGCGAGATGTACCAACAAAAACTGGATTATCAAATTGATATGCTCTCTCAGTTATTAGAGCCAATGTTGATGTTACTGA
TGGGAATAATTGTGGGGACTATTATTGTCGGTTTATATCTACCCATTTTTGATATGGGAAGTTTAGTGGAGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-186)

Type II secretion system (T2SS), protein F (T2SSF)

(266-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

56

100

0.564
  pilC Haemophilus influenzae Rd KW20

41.147

100

0.416
  pilC Haemophilus influenzae 86-028NP

40.15

100

0.406