NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	JH476_RS18175	Genome accession	NZ_CP066836
Coordinates	3792570..3793694 (+)	Length	374 a.a.
NCBI ID	WP_000228540.1	Uniprot ID	-
Organism	Escherichia coli strain Ec-FL1-1X
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3787570..3798694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JH476_RS18150 (JH476_18065)	mscL	3787696..3788106 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
JH476_RS18155 (JH476_18070)	trkA	3788236..3789612 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
JH476_RS18160 (JH476_18075)	rsmB	3789634..3790923 (-)	1290	WP_001309796.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
JH476_RS18165 (JH476_18080)	fmt	3790969..3791916 (-)	948	WP_000004443.1	methionyl-tRNA formyltransferase	-
JH476_RS18170 (JH476_18085)	def	3791931..3792440 (-)	510	WP_000114984.1	peptide deformylase	-
JH476_RS18175 (JH476_18090)	dprA	3792570..3793694 (+)	1125	WP_000228540.1	DNA-protecting protein DprA	Machinery gene
JH476_RS18180 (JH476_18095)	smg	3793666..3794139 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
JH476_RS18185 (JH476_18100)	yrdD	3794168..3794710 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
JH476_RS18190 (JH476_18105)	tsaC	3794715..3795287 (+)	573	WP_001310090.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
JH476_RS18195 (JH476_18110)	aroE	3795292..3796110 (+)	819	WP_000451230.1	shikimate dehydrogenase	-
JH476_RS18200 (JH476_18115)	yrdB	3796107..3796364 (+)	258	WP_001070562.1	DUF1488 domain-containing protein	-
JH476_RS18205 (JH476_18120)	yrdA	3796340..3796894 (-)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41035.00 Da Isoelectric Point: 6.1815

                                >NTDB_id=456550 JH476_RS18175 WP_000228540.1 3792570..3793694(+) (dprA) [Escherichia coli strain Ec-FL1-1X]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSYIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=456550 JH476_RS18175 WP_000228540.1 3792570..3793694(+) (dprA) [Escherichia coli strain Ec-FL1-1X]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGTATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGACGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393
dprA	Legionella pneumophila strain ERS1305867	44.073	87.968	0.388

Detailed information NTG0456550