Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   JDY60_RS06110 Genome accession   NZ_CP066172
Coordinates   1280429..1282330 (-) Length   633 a.a.
NCBI ID   WP_200370341.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1275429..1287330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS06085 (JDY60_06085) - 1275447..1276412 (+) 966 WP_200370335.1 LacI family DNA-binding transcriptional regulator -
  JDY60_RS06090 (JDY60_06090) - 1276562..1277836 (-) 1275 WP_200370337.1 hydroxymethylglutaryl-CoA reductase, degradative -
  JDY60_RS06095 (JDY60_06095) - 1277836..1279008 (-) 1173 WP_200371630.1 hydroxymethylglutaryl-CoA synthase -
  JDY60_RS06100 (JDY60_06100) - 1279127..1279582 (-) 456 WP_000176909.1 threonine/serine exporter family protein -
  JDY60_RS06105 (JDY60_06105) - 1279584..1280342 (-) 759 WP_200370339.1 threonine/serine exporter family protein -
  JDY60_RS06110 (JDY60_06110) stkP 1280429..1282330 (-) 1902 WP_200370341.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  JDY60_RS06115 (JDY60_06115) - 1282327..1283067 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  JDY60_RS06120 (JDY60_06120) rsmB 1283083..1284396 (-) 1314 WP_185758118.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  JDY60_RS06125 (JDY60_06125) fmt 1284389..1285324 (-) 936 WP_200370343.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68873.09 Da        Isoelectric Point: 8.9717

>NTDB_id=453968 JDY60_RS06110 WP_200370341.1 1280429..1282330(-) (stkP) [Streptococcus oralis strain SF100]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGEQVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGHTPSSSSSNNEGSHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=453968 JDY60_RS06110 WP_200370341.1 1280429..1282330(-) (stkP) [Streptococcus oralis strain SF100]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTATA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAACGTGAAGCGAGAGCCATGGCAGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAGTACGTAGCAGGCCTTGACCTCAAGCGTTATATTAAAGAACACTATCC
TCTTTCAAATGAAGAAGCAGTTCGGATTATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCAGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCCGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACCAACTCAATGTTAGGCTCCGTTCATTATTTGTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTGACGGGGCATATCCCTTATGATG
GGGATAGCGCGGTTACGATTGCCCTCCAGCATTTCCAGAAACCACTTCCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATTAAGGCAACTGCTAAGAAGCTGTCAGACCGTTATCAGTCTGTTTCGGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAGCCGGCTCCAGCTCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGTTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTCCTATTCCTG
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCTAAGTTTGAAGCCGGTGAAGAAAAGTCAGAA
GCCAGCGATACCGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGGAAGCAATCCTTCCAATTGAGCAATTACGTCGGACGCAAGTATACGGATGTTGTAGCCG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCTGGAACCGTC
CTCAGACAGACTCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATTGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTAGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGCCAAACGCCA
AGAGCAGGAGAACAGGTTGATCTTGCAAGTACGCGTATCAAACTTTCTATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAACCCTGCCCAACGTGGAAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGCACACTCCTTCTAGCAGTTCATCCAATAATGAAGGATCTCACGAAAGTTCCCGAGATTAA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(372-432)

PASTA domain (PASTA)

(441-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

92.575

0.728
  stkP Streptococcus pneumoniae D39

78.328

92.575

0.725
  stkP Streptococcus pneumoniae R6

78.328

92.575

0.725
  stkP Streptococcus pneumoniae Rx1

78.157

92.575

0.724
  pknB Streptococcus mutans UA159

56.499

91.153

0.515
  stkP/pknB Streptococcus salivarius strain HSISS4

52.445

93.681

0.491