Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   I6I02_RS06845 Genome accession   NZ_CP066093
Coordinates   1508599..1509342 (+) Length   247 a.a.
NCBI ID   WP_002887222.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1503599..1514342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS06820 (I6I02_06820) - 1504234..1504383 (-) 150 Protein_1349 LysR family transcriptional regulator -
  I6I02_RS06825 (I6I02_06825) - 1504393..1505946 (-) 1554 WP_013990980.1 BCCT family transporter -
  I6I02_RS06830 (I6I02_06830) - 1506174..1506785 (-) 612 WP_037602032.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
  I6I02_RS06835 (I6I02_06835) - 1506813..1507028 (-) 216 Protein_1352 CHAP domain-containing protein -
  I6I02_RS10970 - 1507395..1507652 (-) 258 Protein_1353 type II toxin-antitoxin system Phd/YefM family antitoxin -
  I6I02_RS06845 (I6I02_06845) comE/blpR 1508599..1509342 (+) 744 WP_002887222.1 response regulator transcription factor Regulator
  I6I02_RS06850 (I6I02_06850) - 1509352..1510668 (+) 1317 WP_198463307.1 sensor histidine kinase -
  I6I02_RS06855 (I6I02_06855) - 1511831..1512148 (-) 318 Protein_1356 transposase -
  I6I02_RS10975 - 1512420..1513094 (-) 675 Protein_1357 transposase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28700.12 Da        Isoelectric Point: 6.2541

>NTDB_id=453786 I6I02_RS06845 WP_002887222.1 1508599..1509342(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_1045]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIVKINKEEKMVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=453786 I6I02_RS06845 WP_002887222.1 1508599..1509342(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_1045]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATTCGGAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACAGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGAATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGACGACCGCCTATATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAATGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTCTGAAAAGCTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.975

96.761

0.522
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.431

99.595

0.393
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.652

100

0.377
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.652

100

0.377