Detailed information NTG0453615

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: I6H73_RS00340
• Genome accession: NZ_CP066073
• Coordinates: 54025..54465 (+)
• Length: 146 a.a.
• NCBI ID: WP_003058520.1
• Uniprot ID: A0ABU0A7B0
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1016
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 49025..59465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H73_RS00300 (I6H73_00300)	-	50184..50612 (+)	429	WP_003058584.1	DUF1366 domain-containing protein	-
I6H73_RS00305 (I6H73_00305)	-	50578..50805 (+)	228	WP_037588167.1	hypothetical protein	-
I6H73_RS00310 (I6H73_00310)	-	50813..51280 (+)	468	WP_003058491.1	phage holin family protein	-
I6H73_RS00315 (I6H73_00315)	-	51273..51608 (+)	336	WP_003058565.1	phage holin	-
I6H73_RS00320 (I6H73_00320)	-	51610..53055 (+)	1446	WP_003058531.1	peptidoglycan amidohydrolase family protein	-
I6H73_RS00325 (I6H73_00325)	prx	53193..53384 (+)	192	WP_003058494.1	hypothetical protein	Regulator
I6H73_RS00330 (I6H73_00330)	comGD	53399..53791 (+)	393	WP_003058533.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6H73_RS00335 (I6H73_00335)	comGE	53799..54044 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6H73_RS00340 (I6H73_00340)	comGF	54025..54465 (+)	441	WP_003058520.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6H73_RS00345 (I6H73_00345)	comGG	54488..54817 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
I6H73_RS00350 (I6H73_00350)	comGH	54880..55833 (+)	954	WP_003058509.1	class I SAM-dependent methyltransferase	Machinery gene
I6H73_RS00355 (I6H73_00355)	-	55892..57088 (+)	1197	WP_003058485.1	acetate kinase	-
I6H73_RS00360 (I6H73_00360)	-	57394..57600 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
I6H73_RS00365 (I6H73_00365)	-	57703..58383 (+)	681	WP_003058487.1	type II CAAX endopeptidase family protein	-
I6H73_RS00370 (I6H73_00370)	-	58401..58838 (+)	438	WP_003058498.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16968.61 Da
• Isoelectric Point: 10.7829

>NTDB_id=453615 I6H73_RS00340 WP_003058520.1 54025..54465(+) (comGF) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLKRTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=453615 I6H73_RS00340 WP_003058520.1 54025..54465(+) (comGF) [Streptococcus dysgalactiae strain FDAARGOS_1016]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAAAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.201	95.205	0.459
comGF	Streptococcus mutans UA140	47.482	95.205	0.452
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae D39	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis NCTC 12261	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae TIGR4	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae R6	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis SK321	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae Rx1	43.066	93.836	0.404