Detailed information NTG0453580

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6H74_RS08515
• Genome accession: NZ_CP066069
• Coordinates: 1748824..1751067 (-)
• Length: 747 a.a.
• NCBI ID: WP_046176930.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1017
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1743824..1756067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H74_RS08495 (I6H74_08490)	-	1744433..1745653 (+)	1221	WP_015017200.1	DUF3114 domain-containing protein	-
I6H74_RS08500 (I6H74_08495)	-	1745774..1746835 (-)	1062	WP_046176928.1	serine hydrolase	-
I6H74_RS08505 (I6H74_08500)	sodA	1747002..1747607 (-)	606	WP_002983977.1	superoxide dismutase SodA	-
I6H74_RS08510 (I6H74_08505)	holA	1747697..1748743 (-)	1047	WP_115256828.1	DNA polymerase III subunit delta	-
I6H74_RS08515 (I6H74_08510)	comEC/celB	1748824..1751067 (-)	2244	WP_046176930.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6H74_RS08520 (I6H74_08515)	comEA	1751048..1751710 (-)	663	WP_003057999.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6H74_RS08525 (I6H74_08520)	-	1752107..1752847 (-)	741	WP_022554937.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
I6H74_RS08530 (I6H74_08525)	-	1752965..1753741 (+)	777	WP_115257098.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
I6H74_RS08535 (I6H74_08530)	-	1753731..1754009 (+)	279	WP_046176932.1	GIY-YIG nuclease family protein	-
I6H74_RS08540 (I6H74_08535)	-	1754033..1756033 (-)	2001	WP_115256826.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85157.66 Da
• Isoelectric Point: 9.1887

>NTDB_id=453580 I6H74_RS08515 WP_046176930.1 1748824..1751067(-) (comEC/celB) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MNYRWTKWSPLPPIQLAFLVMALYYQIYCPSWLTCLLSSCLGMLLLKQFPQKTLCKVVMILALFAAVFVYWKHQLRQQLE
TQPLQVSQVALVPDSIRINGDQLAVIGRHGNHSYQLFYHFKHQTEARFFQKEYRWIVMHAKIVLDKAETSRNFRGFNYQS
FLAYQGIYRIGKVEQVEQLEVVSPKSVGDYLSSLRRQAIVHCQQSFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRGLTLLAIPLEWIKWIELPFACLYAALTGYSISVIRSLLQAQLGHLGIKGLDNLACAFLLVLL
WDAHALMTVGGVLTFSYAFMLTVITFEELSGVKKHFVQVITVSLGMLPFLLFYFASFNPMSMVLTELLSYLFDVLILPLL
CLVFCLSPLITLSGCNYLFLFLEKVIQFLGNTLNASLVFGSPTSWQLLILVISFAILYDHRKIRQRVITCGLVIGLTLLS
VKYPLTNEVTFIDIGQGDSILVRDWTGKNLLIDVGGRLSFSSKEQWRQGHQTSNAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSQPSFVRRLRGLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGNGKNNDSLVLYGR
LLNQTFLFTGDLEKEGENEIIERYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLTRLEDR
EISYYRTDIQGAVRLTGWLNWHIETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=453580 I6H74_RS08515 WP_046176930.1 1748824..1751067(-) (comEC/celB) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAACTATCGTTGGACTAAGTGGTCTCCCTTGCCTCCCATTCAACTAGCCTTTTTGGTAATGGCTCTTTATTATCAGAT
CTATTGTCCTAGCTGGTTGACTTGCTTACTTAGCAGTTGTTTAGGAATGTTACTATTGAAGCAGTTTCCTCAGAAGACCC
TCTGTAAGGTTGTTATGATTCTGGCCTTATTTGCTGCTGTCTTTGTTTATTGGAAACATCAGTTGAGACAGCAATTGGAA
ACACAACCTTTACAAGTGTCTCAGGTAGCATTGGTTCCGGATAGTATTCGAATTAATGGAGATCAATTAGCTGTTATTGG
GCGTCACGGTAATCATTCTTATCAGTTGTTTTATCATTTTAAACATCAAACGGAAGCCCGATTTTTCCAAAAAGAGTACC
GTTGGATAGTGATGCATGCCAAAATAGTATTGGACAAGGCTGAGACTTCCCGAAATTTTAGAGGATTTAATTACCAATCT
TTTTTAGCCTATCAGGGAATTTACAGGATAGGAAAAGTGGAACAAGTAGAGCAGCTTGAAGTGGTTTCACCAAAGTCAGT
AGGAGATTATTTATCTTCTTTGAGGCGACAGGCTATTGTCCATTGCCAACAATCCTTTCCAAAGCCCATGTCTCATTATT
TGACGGGACTCCTTTTCGGCTATTTGGATAAGTCCTTTGGTGAGATGACAGATTATTATAGTCAGCTTGGTATCATTCAT
CTTTTTGCCCTATCAGGGATGCAGGTTGGCTTCTTTTTAACCTGTTTTAGAAGAGGTTTGACGCTATTAGCTATTCCTCT
CGAATGGATTAAATGGATAGAGCTTCCCTTTGCCTGTCTATATGCTGCGCTGACAGGTTACAGTATTTCTGTTATTCGAA
GCCTTCTGCAGGCCCAATTAGGTCATCTAGGCATAAAAGGCTTAGATAATCTGGCTTGCGCTTTCTTACTTGTTCTTTTA
TGGGATGCTCATGCTTTGATGACTGTTGGTGGAGTACTAACATTTAGCTATGCGTTTATGTTAACTGTTATCACTTTTGA
GGAGTTATCGGGAGTTAAAAAGCATTTCGTCCAGGTCATTACTGTTTCTTTAGGGATGTTACCTTTCTTGCTCTTTTATT
TTGCTAGTTTTAACCCCATGTCAATGGTATTGACAGAGCTTTTGTCTTATCTCTTCGATGTTTTGATTTTGCCTCTTCTT
TGCTTGGTTTTCTGTTTGTCTCCTTTGATAACTCTCTCAGGATGTAATTATCTCTTTCTTTTCTTAGAAAAAGTCATTCA
ATTTCTTGGGAATACCCTCAATGCCTCCCTTGTTTTTGGAAGTCCGACCAGTTGGCAATTGCTTATCCTGGTGATTAGCT
TCGCTATTCTTTATGACCATCGGAAGATACGACAAAGAGTTATCACTTGCGGCTTGGTCATAGGCCTGACACTTTTATCT
GTTAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGCGATAGTATTTTAGTGAGGGATTGGACAGG
AAAAAATCTCTTAATAGATGTAGGTGGGCGCCTTTCCTTTTCTTCAAAAGAGCAGTGGCGACAGGGGCACCAGACATCGA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGCATTCACACCATTGACCAATTACTAGTGACTCATGCGGAT
ACTGATCATATGGGGGATATAGAGGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGCCAAGGTAGTTTAAG
CCAGCCAAGCTTTGTTAGGCGGTTAAGGGGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAATTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTATCCTTGGCAGTTAGGGAACGGGAAAAATAATGATTCTCTGGTTCTTTATGGTAGG
CTCCTCAATCAAACTTTTCTATTTACAGGTGATTTGGAAAAAGAGGGAGAAAACGAGATCATAGAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTGGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCCTAACCCGTTTAGAGGATAGG
GAAATTTCTTATTATCGCACGGATATTCAAGGAGCTGTTCGGTTGACAGGATGGCTAAATTGGCATATTGAGACTGTTCG
TTGA

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

• Competence protein (Competence) (217-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	45.772	99.732	0.456
comEC/celB	Streptococcus mitis NCTC 12261	45.71	99.866	0.456
comEC/celB	Streptococcus pneumoniae TIGR4	45.187	100	0.452
comEC/celB	Streptococcus pneumoniae Rx1	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae D39	44.92	100	0.45
comEC/celB	Streptococcus pneumoniae R6	44.92	100	0.45
comEC	Lactococcus lactis subsp. cremoris KW2	41.588	99.465	0.414