Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   FOC72_RS06725 Genome accession   NZ_CP054570
Coordinates   1413509..1415749 (-) Length   746 a.a.
NCBI ID   WP_002896086.1    Uniprot ID   A0A859ENI6
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1408509..1420749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS06705 (FOC72_06705) - 1409063..1410142 (-) 1080 WP_002934461.1 serine hydrolase -
  FOC72_RS06710 (FOC72_06710) sodA 1410278..1410883 (-) 606 WP_002896081.1 superoxide dismutase SodA -
  FOC72_RS06715 (FOC72_06715) holA 1410946..1411992 (-) 1047 WP_002896082.1 DNA polymerase III subunit delta -
  FOC72_RS06720 (FOC72_06720) - 1412243..1413379 (-) 1137 WP_002896085.1 DUF805 domain-containing protein -
  FOC72_RS06725 (FOC72_06725) comEC/celB 1413509..1415749 (-) 2241 WP_002896086.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FOC72_RS06730 (FOC72_06730) comEA 1415733..1416413 (-) 681 WP_032914217.1 helix-hairpin-helix domain-containing protein Machinery gene
  FOC72_RS06735 (FOC72_06735) - 1416561..1417109 (-) 549 WP_002896088.1 HXXEE domain-containing protein -
  FOC72_RS06740 (FOC72_06740) - 1417182..1417922 (-) 741 WP_002896089.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FOC72_RS06745 (FOC72_06745) - 1418080..1420419 (+) 2340 WP_002896090.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 85047.22 Da        Isoelectric Point: 8.9974

>NTDB_id=453503 FOC72_RS06725 WP_002896086.1 1413509..1415749(-) (comEC/celB) [Streptococcus sanguinis strain FDAARGOS_770]
MSQWIKKLPLAPIYLAFILVWVYFAVYSGSSLAYLGLGVLLLRLFFSYPLKKSLAALAFLSLFVLFFLLRREMAEQAFRQ
EPPSASSVQVLPDTIKFNGDSLSFRGRTDGRLYQVFYKIKSASEKKAFQQLTDLVVLDFEGEFEHAQQQRNFSGFDYQAY
LKSQGIYRTLKINKIQSLRPISSLNPLDWLSVWRRKALVYIRSNFPSPMSHYMTGLLFGDLDTEFAEMSDLYSSLGIIHL
FALSGMQVGFFLDGFRRILLRLGMKRETVNALQLPFSFIYAGLTGFSVSVVRSLVQKLLAQQGLTRLDNFALTLMVLFII
MPNFLLTAGGVLSCAYAFLISMMDFEKLPPIRKLLAESLTISLGILPILIYYFSEFQPWSVILTFLFSLFFDLLILPGLT
LIFILSPLLKITQVNFFFDLLEDVIRWVADFAPRPLIFGKPNLWLLFALLLVLALIYDFRRKKSWLLSFSLLALLLFFLT
KHPLQNEITVVDIGQGDSIFLREWQGRTILIDVGGRVEIGKKEAWQERQTSSNAEKTLIPYLKSRGVASLDVLVLTHTDT
DHMGDMLEVAKHFSIKEIYVSKGSLTQPDFVQKLEQIESSVHVVEVGDEIPVFDSALQVLYPSGTGDGGNDDSIVLYGEF
FQTKFLFTGDLERQGEIELLQRFPQLTADVLKAGHHGSKGSSSPDFLEQIQPKLALISAGQNNRYRHPHQETLQRFEKFN
TAIYRTDQQGAIRLIGWNSWRIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=453503 FOC72_RS06725 WP_002896086.1 1413509..1415749(-) (comEC/celB) [Streptococcus sanguinis strain FDAARGOS_770]
ATGTCACAGTGGATTAAAAAGTTACCCCTAGCCCCTATCTATCTGGCTTTCATTCTTGTATGGGTCTATTTTGCAGTCTA
TTCTGGCAGTTCCTTGGCTTATTTAGGGCTGGGTGTCCTTCTGCTTCGTCTCTTTTTCAGCTATCCCCTCAAAAAAAGTC
TAGCTGCCTTGGCATTCCTGTCCCTTTTTGTCCTCTTTTTCTTGCTTCGTCGGGAAATGGCAGAGCAGGCCTTTAGGCAG
GAACCTCCTTCAGCTAGCTCGGTTCAAGTTTTGCCGGATACGATCAAATTCAATGGAGATTCCCTATCCTTTCGAGGGCG
AACGGACGGTCGGCTTTATCAGGTCTTCTACAAGATCAAATCAGCCAGTGAAAAGAAAGCTTTTCAGCAGCTGACAGATT
TGGTCGTCCTTGATTTTGAAGGAGAGTTTGAACATGCCCAGCAACAACGAAATTTTTCGGGCTTTGACTATCAGGCTTAT
TTAAAGAGTCAGGGAATTTACCGTACCTTAAAAATCAATAAGATTCAGTCACTAAGACCAATTTCCAGCCTGAATCCACT
GGATTGGCTGTCTGTCTGGCGCAGAAAAGCGCTGGTCTATATTCGAAGTAATTTTCCTAGTCCAATGAGCCATTACATGA
CAGGACTCTTGTTTGGTGACTTAGATACGGAGTTTGCGGAAATGAGTGACCTGTATTCTAGCTTGGGTATCATCCATTTG
TTTGCCTTGTCTGGTATGCAGGTAGGTTTCTTTTTGGATGGTTTTCGCAGAATTCTTCTACGTTTGGGGATGAAGAGGGA
GACAGTAAATGCTTTGCAGCTGCCTTTTTCATTTATCTATGCTGGACTCACAGGCTTTTCTGTTTCTGTCGTCAGAAGCT
TAGTTCAGAAGTTGTTGGCCCAGCAAGGACTGACCAGATTAGATAACTTTGCTCTGACACTGATGGTTCTCTTTATCATC
ATGCCCAATTTTCTTCTGACAGCAGGCGGTGTCTTGTCCTGCGCCTATGCCTTTTTGATTTCTATGATGGATTTTGAAAA
GTTACCGCCGATTCGTAAGCTTTTAGCGGAAAGTCTGACTATTTCATTGGGGATTTTGCCTATACTAATCTACTATTTTT
CTGAATTTCAGCCTTGGTCCGTGATTTTAACTTTTTTATTTTCACTATTCTTTGACCTGCTGATACTGCCAGGCTTAACC
CTCATTTTTATTTTGTCACCACTTTTAAAAATCACTCAAGTCAATTTTTTCTTTGACTTACTCGAAGATGTGATTCGTTG
GGTAGCTGATTTTGCTCCGCGCCCTTTGATTTTTGGGAAGCCCAACCTCTGGTTACTGTTCGCTTTGCTTTTGGTTTTGG
CTTTAATCTATGACTTTCGGAGAAAGAAAAGCTGGCTTTTATCTTTTAGTTTGCTTGCTCTTCTCTTATTTTTCCTAACA
AAGCATCCGCTGCAAAATGAGATTACAGTAGTGGATATTGGTCAGGGAGATAGCATTTTTCTCCGGGAATGGCAGGGCAG
GACGATTTTGATTGACGTTGGGGGACGAGTCGAGATAGGAAAGAAAGAGGCTTGGCAGGAGCGACAGACTTCATCCAATG
CAGAAAAGACCTTAATTCCCTATCTCAAAAGTCGTGGTGTTGCTAGTCTGGATGTATTGGTCCTGACTCATACCGATACC
GATCACATGGGAGATATGCTGGAGGTAGCTAAGCATTTTTCCATCAAGGAAATCTATGTTTCCAAAGGAAGTCTCACTCA
GCCTGATTTTGTTCAAAAGCTGGAGCAGATAGAAAGTTCTGTCCATGTCGTAGAAGTGGGAGATGAGATTCCGGTATTTG
ACTCAGCTTTGCAGGTTCTCTATCCTAGTGGGACAGGCGACGGTGGAAATGATGATTCGATTGTACTCTACGGGGAGTTC
TTTCAGACAAAATTTTTGTTTACAGGTGATTTGGAAAGGCAGGGAGAAATTGAACTGCTGCAGCGATTCCCTCAGCTGAC
AGCAGATGTCTTAAAAGCAGGACACCATGGCTCCAAAGGCTCTTCCAGTCCAGATTTTTTAGAGCAAATTCAGCCGAAAC
TGGCCTTGATATCAGCTGGCCAGAATAATCGTTATCGACATCCGCATCAGGAAACTTTGCAAAGATTTGAGAAGTTTAAT
ACAGCCATCTATCGAACTGACCAGCAGGGAGCCATTCGTTTGATTGGTTGGAATTCCTGGAGGATTGAAACGGTACGCTG
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859ENI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

57.831

100

0.579
  comEC/celB Streptococcus mitis NCTC 12261

57.239

100

0.572
  comEC/celB Streptococcus pneumoniae TIGR4

56.627

100

0.567
  comEC/celB Streptococcus pneumoniae Rx1

56.091

100

0.562
  comEC/celB Streptococcus pneumoniae D39

56.091

100

0.562
  comEC/celB Streptococcus pneumoniae R6

56.091

100

0.562
  comEC Lactococcus lactis subsp. cremoris KW2

48.529

100

0.487