Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   FOC72_RS04595 Genome accession   NZ_CP054570
Coordinates   923168..924010 (+) Length   280 a.a.
NCBI ID   WP_002895481.1    Uniprot ID   A0A859EQ24
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 918168..929010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS04565 (FOC72_04565) - 918710..919309 (+) 600 WP_002895471.1 hypothetical protein -
  FOC72_RS04570 (FOC72_04570) - 919555..919893 (+) 339 WP_002895476.1 ATP cone domain-containing protein -
  FOC72_RS04575 (FOC72_04575) ylqF 920035..920886 (+) 852 WP_002895477.1 ribosome biogenesis GTPase YlqF -
  FOC72_RS04580 (FOC72_04580) - 920873..921637 (+) 765 WP_002895478.1 ribonuclease HII -
  FOC72_RS04585 (FOC72_04585) - 921655..922497 (+) 843 WP_002895479.1 PRD domain-containing protein -
  FOC72_RS04590 (FOC72_04590) - 922473..923036 (+) 564 WP_002895480.1 sugar O-acetyltransferase -
  FOC72_RS04595 (FOC72_04595) dprA/cilB/dalA 923168..924010 (+) 843 WP_002895481.1 DNA-processing protein DprA Machinery gene
  FOC72_RS04600 (FOC72_04600) topA 924095..926188 (+) 2094 WP_002895483.1 type I DNA topoisomerase -
  FOC72_RS04605 (FOC72_04605) - 926247..926741 (+) 495 WP_002895485.1 hypothetical protein -
  FOC72_RS04610 (FOC72_04610) trmFO 926835..928169 (+) 1335 WP_002895487.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  FOC72_RS04615 (FOC72_04615) - 928269..928619 (+) 351 WP_002895488.1 DUF1801 domain-containing protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31008.69 Da        Isoelectric Point: 6.7409

>NTDB_id=453494 FOC72_RS04595 WP_002895481.1 923168..924010(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain FDAARGOS_770]
MNNFEIYKMKKAGLTNHQVLNVLRYAESRDGKLSLRDKAVVSECRNPALFIEKYKRLDLPALKEEFELFPSFSILDDIYP
WDLCEIYDAPTLLFYQGNLNLLELPKAAVVGSRDSSKQGNASVQKIIKELNNELVIVSGLARGIDTAAHMAALQNGGQTI
AVIGTGLDVFYPKANKKLQAYIGKNHLLLTEYGPSEQPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGKSDGCHHLIQEGAKCITSGSDVLSEFDF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=453494 FOC72_RS04595 WP_002895481.1 923168..924010(+) (dprA/cilB/dalA) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAATAATTTTGAGATTTATAAAATGAAAAAAGCTGGCTTGACTAATCATCAGGTTTTAAATGTTTTGAGATACGCCGA
GAGTAGAGATGGCAAGCTTTCTCTGCGAGATAAGGCTGTCGTATCTGAGTGCCGCAATCCCGCTCTCTTTATAGAGAAAT
ACAAGAGGCTTGATTTACCAGCTTTGAAGGAAGAATTTGAACTTTTCCCGTCCTTTTCTATCTTGGATGATATTTACCCT
TGGGATTTATGCGAGATTTATGATGCCCCGACTTTGTTATTTTATCAGGGAAATCTAAATCTACTAGAATTGCCCAAGGC
TGCGGTCGTTGGCAGTCGAGACAGCAGTAAGCAAGGAAATGCCTCTGTACAAAAGATTATCAAAGAGCTAAATAATGAAT
TGGTTATCGTCAGCGGCTTGGCTCGTGGGATTGATACAGCGGCTCATATGGCTGCCCTGCAAAACGGAGGTCAGACCATT
GCTGTCATCGGAACAGGATTAGATGTCTTTTATCCTAAGGCAAATAAAAAACTACAAGCTTACATTGGCAAAAATCATTT
ATTATTGACAGAGTATGGTCCAAGTGAACAGCCCTTGAAATTTCATTTTCCAGAGCGGAATCGTATTATCGCCGGTCTCT
GTCGAGGCGTCATCGTGGCAGAAGCTAAGATGCGCTCAGGCAGCCTGATTACCTGTGAGCGAGCGATGGAAGAAGGGCGG
GATGTCTTTGCTATTCCGGGGTCAATTTTAGATGGAAAATCTGACGGTTGCCATCATTTGATTCAAGAGGGTGCAAAGTG
CATCACATCAGGCTCTGACGTCCTATCTGAGTTTGATTTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)

DNA recombination-mediator protein A (DNA_processg_A)

(74-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859EQ24

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.786

100

0.768
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae D39

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae R6

76.429

100

0.764
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

76.429

100

0.764
  dprA/cilB/dalA Streptococcus mitis SK321

76.071

100

0.761
  dprA Streptococcus mutans UA159

67.143

100

0.671
  dprA Lactococcus lactis subsp. cremoris KW2

56.835

99.286

0.564