Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   FOC72_RS01550 Genome accession   NZ_CP054570
Coordinates   318221..320074 (+) Length   617 a.a.
NCBI ID   WP_002893497.1    Uniprot ID   A0A859ERB0
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 313221..325074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS01535 (FOC72_01535) fmt 315224..316159 (+) 936 WP_032913960.1 methionyl-tRNA formyltransferase -
  FOC72_RS01540 (FOC72_01540) rsmB 316149..317465 (+) 1317 WP_002893500.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FOC72_RS01545 (FOC72_01545) - 317484..318224 (+) 741 WP_002893499.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FOC72_RS01550 (FOC72_01550) stkP 318221..320074 (+) 1854 WP_002893497.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FOC72_RS01555 (FOC72_01555) liaF 320219..320914 (+) 696 WP_002893496.1 cell wall-active antibiotics response protein LiaF -
  FOC72_RS01560 (FOC72_01560) - 320911..321930 (+) 1020 WP_002893495.1 sensor histidine kinase -
  FOC72_RS01565 (FOC72_01565) - 321908..322540 (+) 633 WP_002893493.1 response regulator transcription factor -
  FOC72_RS01570 (FOC72_01570) - 322580..323980 (+) 1401 WP_002893492.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FOC72_RS01575 (FOC72_01575) - 323980..324339 (+) 360 WP_002893490.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 67400.24 Da        Isoelectric Point: 6.2773

>NTDB_id=453482 FOC72_RS01550 WP_002893497.1 318221..320074(+) (stkP) [Streptococcus sanguinis strain FDAARGOS_770]
MIQIGKIFAGRYKIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKENSPISNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNVLLTPDGNAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIISENPNVP
QALENVVIKATAKKLTDRYQSVAEMYVDLSSSLSYERRNEKKLVFDDVAKADTKTLPKISPVPQPAVPPVKPTPAKTEAD
EVKEETADAVKKVPKKRRLRTRYKVLFFAVLLVLAAFVVLLYNSPSNTSVPDVSGQTVAEARSAIEAKKLVVGEEKEEYS
DNVESGKVIKTDPQANSQRREGSKIDLIISKGPKTFVMEDYVGQAKSAVVENLKTNYNVSEKLIEIVEEESDEYEPGQVI
RQSPAAGSTYDLTSNHKIKLTVAKEVTSVSMPDFGSMQYTYANARSYLIQMGISSSRIERVVDRSVTSTQADLVTSQSPA
AGQTIDLKSNEKITLYVTEATTPSSSSSSSSSSSSSSKSSSSSEDSGHGTSSSSSDS

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=453482 FOC72_RS01550 WP_002893497.1 318221..320074(+) (stkP) [Streptococcus sanguinis strain FDAARGOS_770]
ATGATTCAAATCGGCAAAATCTTTGCCGGGCGATATAAAATTATCAAGCAGATTGGCCGCGGAGGTATGGCAGATGTCTA
TCTGGCCAAAGACTTGATTTTGGATGGTGAGGAAGTTGCGGTAAAGGTTCTTAGGACCAATTACCAGACAGATCCTATCG
CTGTCGCGCGTTTCCAGCGGGAAGCTAAGGCGATGGCTGACTTGGACCATCCGCACATCGTTCGGATTACTGATATTGGG
GAAGAAGATGGCCAGCAGTATCTGGCTATGGAATACGTGGCAGGTCTTGACCTCAAGCGCTATATCAAAGAGAATTCTCC
GATTTCAAATGAAGAAGCAGTCAGAATCATGGGACAAATCTTGCTGGCGATGCGCTTGGCGCATACACGCGGTATTGTCC
ATCGTGACCTGAAACCACAAAATGTCCTCTTGACCCCAGATGGCAATGCCAAGGTAACAGACTTTGGAATTGCGGTGGCC
TTTGCGGAGACAAGTCTGACTCAGACTAACTCAATGCTGGGCTCGGTTCATTATCTATCGCCTGAGCAGGCACGTGGCTC
TAAAGCAACTGTTCAGAGTGATATTTATGCGATGGGGATTATTTTTTATGAGATGCTGACTGGTCATATCCCTTATGATG
GGGATAGTGCCGTTACGATTGCTCTTCAGCATTTCCAAAAGCCGCTGCCATCCATCATTTCTGAAAATCCTAATGTGCCT
CAGGCCTTGGAAAATGTGGTCATTAAGGCAACAGCCAAAAAACTGACGGATCGCTATCAGTCAGTTGCAGAGATGTATGT
TGACTTGTCCAGCAGCTTATCTTATGAGCGCCGGAATGAAAAGAAATTAGTCTTTGATGATGTTGCGAAAGCAGACACCA
AGACCTTGCCAAAAATCTCACCTGTACCGCAGCCGGCAGTTCCACCTGTTAAGCCAACTCCGGCTAAAACGGAAGCGGAT
GAAGTTAAGGAAGAGACAGCTGATGCGGTTAAGAAAGTTCCAAAGAAACGTCGTTTGAGAACGCGTTACAAGGTTCTTTT
CTTTGCAGTCCTATTGGTTTTGGCGGCTTTTGTTGTCCTTCTTTATAATAGCCCATCCAATACCAGCGTGCCAGATGTTT
CTGGTCAGACTGTGGCAGAGGCTCGCTCCGCTATCGAAGCTAAGAAGCTGGTTGTCGGAGAGGAGAAGGAAGAATACAGT
GACAATGTTGAATCTGGCAAAGTCATTAAAACTGATCCACAGGCAAATAGTCAGCGCCGCGAAGGCAGCAAGATTGACCT
GATTATCTCCAAGGGACCCAAGACCTTTGTGATGGAAGATTATGTCGGACAAGCAAAATCAGCCGTGGTTGAAAATCTGA
AAACAAACTATAATGTTTCTGAGAAATTGATTGAGATTGTTGAGGAAGAATCGGACGAGTACGAGCCAGGTCAGGTGATT
CGTCAGTCTCCGGCAGCTGGTTCGACCTATGATTTGACTTCTAATCATAAGATTAAGCTGACAGTGGCGAAAGAAGTGAC
TAGTGTGTCCATGCCTGACTTTGGCAGCATGCAGTACACCTACGCCAATGCACGGTCTTACTTGATCCAAATGGGAATTT
CTTCTTCCCGAATTGAGCGAGTTGTTGACCGTTCGGTCACTTCGACTCAGGCAGACTTGGTAACTTCCCAGTCACCAGCA
GCAGGTCAGACAATCGATCTCAAGTCTAATGAAAAAATCACTCTTTACGTGACAGAAGCAACAACACCATCGTCATCTAG
TTCGTCATCATCATCGTCTAGCAGTAGCTCAAAGAGCAGCTCATCGTCTGAAGATAGTGGACATGGAACAAGTTCTAGCT
CATCTGATAGTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(510-578)

PASTA domain (PASTA)

(437-504)

PASTA domain (PASTA)

(370-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859ERB0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.427

98.379

0.624
  stkP Streptococcus pneumoniae D39

63.097

98.379

0.621
  stkP Streptococcus pneumoniae R6

63.097

98.379

0.621
  stkP Streptococcus pneumoniae Rx1

62.932

98.379

0.619
  pknB Streptococcus mutans UA159

58.092

95.138

0.553
  stkP/pknB Streptococcus salivarius strain HSISS4

56.134

96.434

0.541