Detailed information NTG0452421

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: HTZ88_RS08700
• Genome accession: NZ_CP054418
• Coordinates: 1701864..1704017 (-)
• Length: 717 a.a.
• NCBI ID: WP_305068180.1
• Uniprot ID: -
• Organism: Leuconostoc carnosum strain 4010
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1696864..1709017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HTZ88_RS08675 (HTZ88_08605)	-	1697683..1698186 (+)	504	WP_135197918.1	nitroreductase family protein	-
HTZ88_RS08680 (HTZ88_08610)	-	1698449..1698904 (+)	456	Protein_1653	nucleoside hydrolase	-
HTZ88_RS08685 (HTZ88_08615)	-	1699064..1699741 (-)	678	WP_135197919.1	CPBP family intramembrane glutamic endopeptidase	-
HTZ88_RS08690 (HTZ88_08620)	-	1700222..1700482 (-)	261	WP_135197920.1	helix-turn-helix domain-containing protein	-
HTZ88_RS08695 (HTZ88_08625)	-	1700475..1701851 (-)	1377	WP_135197921.1	bacteriocin secretion accessory protein	-
HTZ88_RS08700 (HTZ88_08630)	comA	1701864..1704017 (-)	2154	WP_305068180.1	peptide cleavage/export ABC transporter	Regulator
HTZ88_RS08705 (HTZ88_08635)	-	1704432..1704578 (-)	147	WP_172600989.1	hypothetical protein	-
HTZ88_RS08710 (HTZ88_08640)	-	1704620..1704784 (-)	165	WP_172600990.1	hypothetical protein	-
HTZ88_RS08715 (HTZ88_08645)	-	1704977..1705756 (+)	780	WP_172600991.1	CPBP family intramembrane glutamic endopeptidase	-
HTZ88_RS08720	-	1705816..1705950 (+)	135	WP_263317040.1	hypothetical protein	-
HTZ88_RS08725 (HTZ88_08650)	-	1706104..1707003 (-)	900	WP_135197923.1	PhzF family isomerase	-
HTZ88_RS08730 (HTZ88_08655)	-	1707152..1707289 (-)	138	WP_172600992.1	hypothetical protein	-
HTZ88_RS08735 (HTZ88_08660)	-	1707319..1707848 (+)	530	Protein_1664	recombinase family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 79455.40 Da
• Isoelectric Point: 5.3096

>NTDB_id=452421 HTZ88_RS08700 WP_305068180.1 1701864..1704017(-) (comA) [Leuconostoc carnosum strain 4010]
MFIKKINYIPQVDERDCGVAAVAMIMAHYSTRMSLARLREIAKTDMEGTTALGIVKAAQALDFDTMPVQADLSMFDKKDL
PYPFIAHVQKDGKYPHYYVVYGMKGKNLLIADPDITVGRTKMAKSYFANEWTGVAIFIAPNPTYKPTKDKKRSLSSFIPV
IVKQRGLVTNIVIAALMVTLVSILGSYYLQGIIDTYIPDNMKSTLGVVSVGLIVAYVIQQMLSYARDYLLIIMGQRLSID
IILSYIKHIFELPMSFFATRRTGEIISRFTDANAIIEALASKMLSLFLDVGILVIVGTVLVIQNPTLFLISLVAVPAYSL
VIWLFMKPFSKMNNDQMQAGAMLSASIIEDINGVETIKALNSEQVAYKKVDHEFVTYLDKSFIYAKTEAVQNALKSLLHL
ILNVLVLWVGSQLVMDNKISMGQLITYNALLGFFTDPLQNIINLQTKLQQASVANNRLNEVYLVESEYKEQSALSEEIAD
ASDINMTQVTYKYGFGAPAIDDVSLQIESGEKVALVGVSGSGKSTLVKLLVNFFQPESGTIMIGNSTLENIDKHELRSYI
NYLPQEPYIFTGSIIENLMLGANPGTTQADIIRATELAEIKDDIENMSQGFSTELAESGNISGGQKQRIALARALLVDSP
VLILDESTSNLDVLTEKKIIDNLMKLTDKTIIFVAHRLTVSQKVQRIIAMQSGKIIEDGSHDELLEQAGFYASLFND

Nucleotide

• Length: 2154 bp

>NTDB_id=452421 HTZ88_RS08700 WP_305068180.1 1701864..1704017(-) (comA) [Leuconostoc carnosum strain 4010]
ATGTTTATCAAAAAAATTAATTACATACCGCAAGTTGATGAACGTGATTGTGGGGTGGCAGCGGTAGCCATGATTATGGC
GCATTATAGTACACGAATGTCCTTAGCACGATTACGTGAAATAGCCAAGACAGACATGGAGGGAACGACAGCATTAGGAA
TTGTTAAGGCAGCACAAGCGCTTGATTTCGATACAATGCCAGTTCAGGCAGATCTATCTATGTTTGATAAGAAAGACTTA
CCTTATCCATTTATTGCACATGTTCAAAAAGATGGCAAGTATCCACATTATTACGTTGTTTATGGTATGAAGGGGAAAAA
TCTATTAATTGCTGATCCTGATATTACCGTTGGTAGGACTAAAATGGCAAAATCTTATTTTGCTAATGAATGGACTGGTG
TCGCCATATTTATTGCTCCCAATCCAACTTATAAACCAACCAAAGATAAGAAACGCTCGTTAAGCTCTTTTATACCGGTT
ATCGTTAAGCAACGTGGATTGGTGACTAATATTGTAATCGCGGCACTTATGGTGACTTTGGTCAGTATTTTAGGATCTTA
TTATTTGCAGGGAATTATTGATACCTATATACCAGATAATATGAAGAGCACGCTGGGTGTTGTATCTGTCGGTTTAATTG
TAGCCTATGTGATACAGCAGATGTTGTCATATGCCAGAGATTACTTATTAATTATCATGGGTCAACGATTATCAATTGAT
ATTATTCTGTCCTATATTAAGCATATTTTTGAATTACCGATGTCTTTTTTTGCAACAAGACGGACCGGAGAAATTATTAG
CCGTTTCACTGATGCGAATGCTATTATTGAAGCCTTGGCTAGTAAAATGTTGTCCTTGTTTTTAGATGTTGGCATATTAG
TTATAGTTGGAACAGTATTAGTGATTCAAAATCCAACGTTATTTTTGATTTCATTAGTAGCAGTACCAGCATATTCTTTA
GTGATATGGCTCTTTATGAAGCCGTTTTCTAAGATGAATAATGATCAAATGCAAGCTGGGGCAATGTTGAGCGCTTCAAT
CATAGAAGACATTAATGGTGTCGAAACGATTAAAGCATTGAACAGTGAACAAGTTGCGTATAAAAAAGTTGATCATGAAT
TTGTCACGTATTTAGATAAGTCATTTATCTATGCCAAAACTGAAGCGGTTCAAAATGCACTTAAGAGTTTATTGCACTTA
ATTTTGAATGTTTTAGTTCTTTGGGTTGGCTCACAATTGGTTATGGATAACAAAATAAGCATGGGTCAGCTGATCACATA
TAATGCTCTACTTGGATTTTTTACAGATCCATTACAAAACATTATCAACTTACAAACTAAGTTGCAACAAGCTTCAGTTG
CTAATAATCGCTTAAATGAAGTGTACTTAGTTGAGTCAGAATATAAAGAACAGTCCGCATTAAGTGAAGAAATCGCAGAT
GCTAGTGATATCAATATGACACAGGTGACTTATAAATACGGCTTTGGTGCACCTGCGATTGATGATGTGTCACTTCAAAT
TGAATCAGGTGAAAAAGTTGCCTTGGTTGGTGTGAGCGGTTCGGGGAAATCAACATTAGTGAAATTGTTAGTTAATTTTT
TCCAGCCGGAATCAGGCACAATCATGATAGGGAATAGTACATTAGAAAATATTGATAAACATGAATTACGCTCGTATATT
AATTACCTCCCACAAGAGCCGTATATTTTTACAGGTTCAATTATTGAAAATTTGATGTTAGGTGCAAATCCTGGAACAAC
ACAAGCGGATATTATACGCGCGACTGAATTAGCTGAAATTAAAGACGATATTGAAAACATGTCACAAGGATTTAGTACAG
AATTAGCTGAGAGTGGGAATATTTCAGGTGGTCAAAAACAGCGGATTGCTTTAGCACGCGCTCTGCTGGTTGATTCACCC
GTCTTAATTCTTGATGAATCGACTAGTAATTTAGATGTATTAACTGAAAAGAAGATTATTGATAATTTAATGAAGTTAAC
TGATAAAACGATTATTTTTGTGGCGCATCGTCTGACCGTATCACAAAAAGTACAGCGCATTATTGCTATGCAATCAGGTA
AAATAATTGAAGACGGGTCTCATGATGAATTACTAGAACAAGCGGGCTTCTATGCCTCTTTGTTTAATGATTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• ABC transporter (ABC_tran) (501-649)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	60.112	100	0.601
comA	Streptococcus gordonii str. Challis substr. CH1	59.833	100	0.598
comA	Streptococcus mitis SK321	59.693	100	0.597
comA	Streptococcus pneumoniae Rx1	59.275	100	0.593
comA	Streptococcus pneumoniae D39	59.275	100	0.593
comA	Streptococcus pneumoniae R6	59.275	100	0.593
comA	Streptococcus pneumoniae TIGR4	59.135	100	0.591
comA/nlmT	Streptococcus mutans UA159	58.192	98.745	0.575