Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HTZ88_RS08110 Genome accession   NZ_CP054418
Coordinates   1586774..1587913 (-) Length   379 a.a.
NCBI ID   WP_135197846.1    Uniprot ID   -
Organism   Leuconostoc carnosum strain 4010     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1581774..1592913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HTZ88_RS08085 (HTZ88_08020) mutY 1581861..1582883 (-) 1023 WP_150289867.1 A/G-specific adenine glycosylase -
  HTZ88_RS08090 (HTZ88_08025) - 1583007..1583150 (+) 144 WP_014974929.1 hypothetical protein -
  HTZ88_RS08095 (HTZ88_08030) - 1583290..1584687 (+) 1398 WP_014974930.1 DHA2 family efflux MFS transporter permease subunit -
  HTZ88_RS08100 (HTZ88_08035) thiD 1584754..1585563 (-) 810 WP_135197844.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  HTZ88_RS08105 (HTZ88_08040) rlmH 1585641..1586120 (-) 480 WP_135197845.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HTZ88_RS08110 (HTZ88_08045) htrA 1586774..1587913 (-) 1140 WP_135197846.1 S1C family serine protease Regulator
  HTZ88_RS08115 (HTZ88_08050) yycI 1587977..1588762 (-) 786 WP_135197847.1 two-component system regulatory protein YycI -
  HTZ88_RS08120 (HTZ88_08055) yycH 1588793..1590097 (-) 1305 WP_135197848.1 two-component system activity regulator YycH -
  HTZ88_RS08125 (HTZ88_08060) walK 1590087..1591958 (-) 1872 WP_014974936.1 cell wall metabolism sensor histidine kinase WalK -
  HTZ88_RS08130 (HTZ88_08065) yycF 1592090..1592797 (-) 708 WP_014974937.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39605.04 Da        Isoelectric Point: 9.6237

>NTDB_id=452418 HTZ88_RS08110 WP_135197846.1 1586774..1587913(-) (htrA) [Leuconostoc carnosum strain 4010]
MKQYSLTKIVLTGIIAGVIGGGALLYGQRGVENLQTSTQKVNTKASETSTIPKNATATTAYDKISDAVVSVLNFSQTGQR
RYEESSEGSGVIYKKAGDSAYIVTNNHVISGASKIQVMMHDGKKVEASLVGKDIMTDLAVLKMDAKNVTATASFGDSNKI
QVGQKVLAIGSPLGSQYASSVTQGIISAKKRLVEASSENGQSYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSSSGTSVEGMGFAIPSDQVVNIVNELVKNGKITRPAIGISLVELSEITVDDQKTLLKIPETVTGGVVVMGTTDNGPAAK
AGLKKYDVITAIEGKTVAGQADLREELYKHKLGDTISVTYYHQATKHTVNIKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=452418 HTZ88_RS08110 WP_135197846.1 1586774..1587913(-) (htrA) [Leuconostoc carnosum strain 4010]
ATGAAACAATATTCATTAACAAAAATCGTATTAACTGGTATCATCGCCGGTGTTATCGGTGGTGGCGCATTATTATATGG
GCAACGCGGTGTTGAAAATTTGCAAACATCGACACAAAAGGTTAACACAAAGGCTAGTGAAACTAGTACTATCCCCAAAA
ACGCTACAGCCACAACGGCTTATGATAAAATCTCTGATGCAGTTGTTTCAGTATTAAATTTTTCACAAACTGGTCAGAGA
CGCTATGAAGAGTCATCTGAAGGTTCTGGTGTGATTTACAAGAAAGCCGGCGATTCAGCCTATATCGTGACCAATAATCA
CGTGATTAGCGGTGCCTCTAAGATTCAAGTGATGATGCATGATGGTAAAAAGGTTGAAGCATCATTAGTCGGCAAAGATA
TCATGACTGATTTAGCTGTTTTAAAAATGGATGCCAAAAATGTGACGGCAACGGCATCATTTGGTGATTCAAATAAAATC
CAAGTTGGTCAAAAGGTGTTAGCTATCGGTTCTCCCCTGGGTTCACAGTACGCCTCTTCAGTGACTCAAGGTATCATTTC
TGCCAAAAAACGTTTAGTTGAGGCGAGCTCTGAAAACGGGCAAAGTTATGGTGGATCAACAGTTATTCAAACAGATGCTG
CCATTAATCCTGGTAACTCAGGTGGACCACTGATTAATTTTGCAGGTCAAGTCATTGGGATTAACTCAATGAAGTTATCC
TCCTCCTCATCTGGTACGAGCGTTGAAGGGATGGGATTTGCAATACCTTCAGATCAGGTGGTTAACATTGTCAATGAACT
GGTGAAGAATGGTAAAATCACAAGGCCGGCTATTGGTATTAGCTTAGTCGAACTTTCCGAAATAACGGTTGATGACCAAA
AAACTTTACTGAAAATTCCAGAAACTGTAACAGGTGGTGTCGTGGTCATGGGCACGACGGATAATGGGCCGGCAGCTAAA
GCTGGTTTGAAGAAGTACGACGTGATTACTGCTATTGAAGGTAAAACAGTGGCTGGTCAAGCAGACTTGCGTGAGGAGCT
CTACAAGCATAAATTAGGAGACACAATCAGCGTAACCTACTATCACCAAGCAACCAAGCACACAGTCAATATTAAATTAA
CACAGAAATTAGGAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Peptidase family M50 (Peptidase_M50)

(41-375)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.044

100

0.483
  htrA Streptococcus mutans UA159

52.353

89.71

0.47
  htrA Streptococcus gordonii str. Challis substr. CH1

46.438

100

0.464
  htrA Streptococcus pneumoniae TIGR4

50.729

90.501

0.459
  htrA Streptococcus pneumoniae D39

50.729

90.501

0.459
  htrA Streptococcus pneumoniae Rx1

50.729

90.501

0.459
  htrA Streptococcus pneumoniae R6

50.729

90.501

0.459