Detailed information NTG0045176

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: SDSE_RS11315
• Genome accession: NC_019042
• Coordinates: 114886..115326 (+)
• Length: 146 a.a.
• NCBI ID: WP_003058520.1
• Uniprot ID: A0ABU0A7B0
• Organism: Streptococcus dysgalactiae subsp. equisimilis AC-2713
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 109886..120326

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SDSE_RS11285 (S_dysgal_equisimilis_AC2713_169)	-	111567..111932 (+)	366	WP_003055257.1	DUF1033 family protein	-
SDSE_RS11290 (S_dysgal_equisimilis_AC2713_170)	comGA/cglA	112013..112954 (+)	942	WP_003055265.1	competence type IV pilus ATPase ComGA	Machinery gene
SDSE_RS11295 (S_dysgal_equisimilis_AC2713_171)	comGB	112890..113921 (+)	1032	WP_015057201.1	competence type IV pilus assembly protein ComGB	Machinery gene
SDSE_RS11300 (S_dysgal_equisimilis_AC2713_172)	comGC	113923..114249 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
SDSE_RS11305 (S_dysgal_equisimilis_AC2713_173)	comGD	114224..114652 (+)	429	WP_041781473.1	competence type IV pilus minor pilin ComGD	Machinery gene
SDSE_RS11310 (S_dysgal_equisimilis_AC2713_174)	comGE	114660..114905 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
SDSE_RS11315 (S_dysgal_equisimilis_AC2713_175)	comGF	114886..115326 (+)	441	WP_003058520.1	competence type IV pilus minor pilin ComGF	Machinery gene
SDSE_RS11320 (S_dysgal_equisimilis_AC2713_176)	comGG	115349..115678 (+)	330	WP_003058539.1	competence type IV pilus minor pilin ComGG	-
SDSE_RS11325 (S_dysgal_equisimilis_AC2713_177)	comGH	115741..116694 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
SDSE_RS11330 (S_dysgal_equisimilis_AC2713_178)	-	116753..117949 (+)	1197	WP_015057203.1	acetate kinase	-
SDSE_RS11335 (S_dysgal_equisimilis_AC2713_179)	-	118255..118461 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
SDSE_RS11340 (S_dysgal_equisimilis_AC2713_180)	-	118564..119244 (+)	681	WP_012766451.1	type II CAAX endopeptidase family protein	-
SDSE_RS11345 (S_dysgal_equisimilis_AC2713_181)	-	119262..119699 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16968.61 Da
• Isoelectric Point: 10.7829

>NTDB_id=45176 SDSE_RS11315 WP_003058520.1 114886..115326(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLKRTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=45176 SDSE_RS11315 WP_003058520.1 114886..115326(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAAAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.201	95.205	0.459
comGF	Streptococcus mutans UA140	47.482	95.205	0.452
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae D39	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis NCTC 12261	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae TIGR4	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae R6	43.066	93.836	0.404
comGF/cglF	Streptococcus mitis SK321	43.066	93.836	0.404
comGF/cglF	Streptococcus pneumoniae Rx1	43.066	93.836	0.404