Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I6H01_RS10630 Genome accession   NZ_CP065613
Coordinates   2184072..2185196 (-) Length   374 a.a.
NCBI ID   WP_000228504.1    Uniprot ID   B2U2Q3
Organism   Escherichia coli strain FDAARGOS_944     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2179072..2190196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H01_RS10600 (I6H01_10600) yrdA 2180872..2181426 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  I6H01_RS10605 (I6H01_10605) yrdB 2181402..2181659 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  I6H01_RS10610 (I6H01_10610) aroE 2181656..2182474 (-) 819 WP_000451211.1 shikimate dehydrogenase -
  I6H01_RS10615 (I6H01_10615) tsaC 2182479..2183051 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  I6H01_RS10620 (I6H01_10620) yrdD 2183056..2183598 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  I6H01_RS10625 (I6H01_10625) smg 2183627..2184100 (-) 474 WP_000460668.1 DUF494 family protein Smg -
  I6H01_RS10630 (I6H01_10630) dprA 2184072..2185196 (-) 1125 WP_000228504.1 DNA-protecting protein DprA Machinery gene
  I6H01_RS10635 (I6H01_10635) def 2185326..2185835 (+) 510 WP_000114984.1 peptide deformylase -
  I6H01_RS10640 (I6H01_10640) fmt 2185850..2186797 (+) 948 WP_038340802.1 methionyl-tRNA formyltransferase -
  I6H01_RS10645 (I6H01_10645) rsmB 2186843..2188132 (+) 1290 WP_001613941.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H01_RS10650 (I6H01_10650) trkA 2188154..2189530 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  I6H01_RS10655 (I6H01_10655) mscL 2189660..2189866 (+) 207 Protein_2093 large conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40993.95 Da        Isoelectric Point: 6.3837

>NTDB_id=450233 I6H01_RS10630 WP_000228504.1 2184072..2185196(-) (dprA) [Escherichia coli strain FDAARGOS_944]
MVDTDIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=450233 I6H01_RS10630 WP_000228504.1 2184072..2185196(-) (dprA) [Escherichia coli strain FDAARGOS_944]
ATGGTCGATACAGATATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CCACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAACGGACTTAATACCATTCATCCGCGCCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGTTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B2U2Q3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.652

100

0.447
  dprA Vibrio cholerae strain A1552

44.652

100

0.447
  dprA Haemophilus influenzae Rd KW20

45.104

90.107

0.406
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39