Detailed information NTG0450166

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FOC63_RS07545
• Genome accession: NZ_CP054015
• Coordinates: 1468432..1470663 (+)
• Length: 743 a.a.
• NCBI ID: WP_043878536.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain FDAARGOS_755
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1463432..1475663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC63_RS07520 (FOC63_07520)	-	1464193..1465773 (+)	1581	WP_009853763.1	DEAD/DEAH box helicase	-
FOC63_RS07525 (FOC63_07525)	-	1465817..1466089 (-)	273	WP_009853764.1	GIY-YIG nuclease family protein	-
FOC63_RS07530 (FOC63_07530)	-	1466064..1466825 (-)	762	WP_009853765.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FOC63_RS07535 (FOC63_07535)	-	1466933..1467679 (+)	747	WP_009853766.1	lysophospholipid acyltransferase family protein	-
FOC63_RS07540 (FOC63_07540)	comEA	1467774..1468439 (+)	666	WP_009853767.1	helix-hairpin-helix domain-containing protein	Machinery gene
FOC63_RS07545 (FOC63_07545)	comEC/celB	1468432..1470663 (+)	2232	WP_043878536.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FOC63_RS07550 (FOC63_07550)	holA	1470737..1471774 (+)	1038	WP_009853769.1	DNA polymerase III subunit delta	-
FOC63_RS07555 (FOC63_07555)	sodA	1471863..1472471 (+)	609	WP_014619989.1	superoxide dismutase SodA	-
FOC63_RS07560 (FOC63_07560)	-	1472623..1473348 (+)	726	WP_012961667.1	YebC/PmpR family DNA-binding transcriptional regulator	-
FOC63_RS07565 (FOC63_07565)	queA	1473380..1474408 (-)	1029	WP_009853772.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
FOC63_RS07570 (FOC63_07570)	-	1474584..1475084 (+)	501	WP_009853773.1	VIT1/CCC1 transporter family protein	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83699.00 Da
• Isoelectric Point: 8.3630

>NTDB_id=450166 FOC63_RS07545 WP_043878536.1 1468432..1470663(+) (comEC/celB) [Streptococcus gallolyticus strain FDAARGOS_755]
MIKYFPIKPIQLAFLLILLYYFCFSKVIGCLMFLLLALVFLWQQYGWKAWCQVCLCLSCFAVFFLTKSNQTEQAYQAAPA
HLAKIQMIPDTISVNGDLLSFRGKEAGRTYQIFYTLKSEKEQHFFKTLNQTVVLSGDMDLEEATPQRNFGGFDYRTYLKH
EGIYRVVNLSAINNVELVYKMTLWEKLHDVRRKAIVSIQQHFPAPMQHYMTGLLFGYLDKSFDEMSDVYTSLGIIHLFAL
SGMQVGFFVGAFRFFFLRLGLRRDYVDILQIPFSLVYAGLTGFSVSVIRSLIQSAFANLGIKKLDNLALTLFVLFIVMPN
FLLTTGGILSFTYAFILSFINFDDISRYQKIIAESLTISLASLPLLIHFFAVFQPLSVLLTAIFSVAFDTIMLPMLSIVF
ILSPLVKLTCFNGCFVFLETVIKNTKAILGGPIVFGKPSLGILVLLFLTLGVLYDCWRRKKMAIFLVSLVGLLFFQIKHP
LENEVTVVDIGQGDSIFVRDVKGHTLLIDVGGKVSFSEKNAWQERLTDSNAERTLIPYLNSRGVGKIDQLVLTHTDTDHM
GDMLEVAKQVKIGEILVSQGSLTKPDFVAKLQAMKTKVHVVTAGDVLPIMGSHLQVLYPSQTGDGGNNDSVVLYGNLLGK
NFLFTGDLEEEGEQELIATYPNLPVDVLKAGHHGSKGSSSSEFLAHISPQIALISAGQNNRYKHPHQETLERFRAQNMTI
YRTDEQGAIRFRGLNHWKIETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=450166 FOC63_RS07545 WP_043878536.1 1468432..1470663(+) (comEC/celB) [Streptococcus gallolyticus strain FDAARGOS_755]
TTGATTAAATATTTTCCCATTAAGCCAATTCAATTGGCTTTTTTGCTCATTTTGCTCTATTATTTTTGCTTTTCAAAAGT
GATTGGGTGTTTGATGTTTCTCTTGCTAGCCTTGGTGTTTTTATGGCAACAGTATGGTTGGAAGGCTTGGTGTCAAGTTT
GCTTGTGTTTAAGCTGTTTTGCGGTATTTTTTCTGACTAAGTCTAATCAGACAGAGCAGGCTTATCAAGCAGCACCAGCT
CATTTAGCAAAAATCCAGATGATTCCTGACACGATTTCGGTCAATGGGGATTTGCTGTCCTTTCGAGGTAAGGAAGCTGG
GCGGACTTATCAGATTTTTTATACCTTGAAATCGGAGAAAGAACAGCATTTTTTTAAGACATTAAATCAAACGGTTGTTT
TATCTGGTGATATGGACTTGGAAGAAGCAACGCCCCAGCGGAATTTTGGTGGTTTTGATTATCGTACTTACCTTAAACAT
GAAGGCATTTATCGTGTGGTAAATTTGTCGGCGATTAACAATGTTGAACTTGTTTATAAGATGACTTTGTGGGAGAAGCT
ACATGATGTTCGGCGAAAGGCTATTGTTAGTATTCAGCAACATTTTCCTGCTCCTATGCAACATTATATGACTGGGCTTT
TGTTTGGCTATCTGGATAAATCGTTTGATGAGATGAGTGATGTTTACACGAGTTTAGGAATTATTCACCTCTTTGCTCTT
TCAGGCATGCAGGTCGGCTTTTTTGTGGGGGCATTCCGCTTTTTCTTTCTACGTCTTGGGTTACGCCGAGATTATGTGGA
CATACTACAAATTCCATTTTCACTCGTCTATGCGGGGCTGACTGGCTTTTCTGTTTCGGTGATTCGGAGTTTAATTCAAT
CTGCTTTTGCAAATCTTGGTATTAAAAAATTAGATAACTTAGCTTTAACTTTGTTTGTTCTTTTCATAGTTATGCCAAAT
TTTCTGCTGACGACGGGAGGCATTCTTTCGTTTACTTACGCTTTTATTCTCAGTTTTATTAACTTTGATGACATTAGTCG
CTATCAGAAAATCATTGCGGAAAGTTTGACGATTTCATTAGCCAGTTTGCCCTTGTTAATTCATTTTTTTGCTGTGTTTC
AACCGTTATCTGTCTTATTGACAGCAATTTTTTCTGTGGCATTTGACACTATTATGTTGCCAATGCTATCAATCGTTTTT
ATTTTATCGCCCTTGGTTAAACTGACTTGTTTTAATGGTTGTTTTGTTTTCTTGGAAACTGTTATCAAGAACACTAAGGC
AATTTTGGGCGGTCCGATTGTTTTTGGTAAACCAAGTCTTGGTATCTTGGTGCTACTATTTTTAACATTAGGCGTGCTTT
ATGATTGCTGGCGACGAAAGAAAATGGCAATTTTTCTTGTCAGCTTAGTAGGTCTGCTATTTTTTCAAATCAAGCATCCG
CTAGAAAACGAGGTGACGGTGGTTGATATTGGGCAGGGAGATAGTATTTTTGTGCGTGATGTTAAGGGGCATACGCTGCT
AATTGATGTGGGCGGAAAGGTGAGTTTTAGTGAGAAGAACGCGTGGCAGGAGCGGCTGACGGATAGCAATGCGGAGCGAA
CGTTGATTCCTTATCTCAACAGTCGCGGCGTTGGAAAAATTGACCAGTTAGTTCTGACGCACACGGATACTGACCACATG
GGAGATATGCTGGAAGTGGCAAAGCAGGTGAAAATTGGTGAAATTCTGGTTAGTCAGGGAAGTTTGACAAAACCAGATTT
TGTGGCGAAATTACAAGCCATGAAAACCAAGGTGCACGTGGTAACAGCTGGTGATGTTTTGCCGATTATGGGAAGTCACC
TGCAAGTGCTTTATCCGAGCCAGACTGGTGATGGTGGTAACAATGACTCGGTGGTGCTTTATGGGAATCTTTTGGGTAAG
AATTTCTTATTTACAGGAGATTTGGAAGAAGAAGGCGAGCAAGAGTTGATAGCAACTTATCCCAATCTGCCGGTTGATGT
CTTAAAAGCAGGACATCATGGCTCAAAAGGGTCATCAAGCTCAGAATTTCTCGCTCACATTTCACCGCAAATTGCTTTGA
TTTCCGCAGGGCAAAATAACCGCTACAAACATCCTCATCAAGAAACGCTTGAACGCTTCCGAGCACAAAACATGACCATT
TACCGTACAGACGAACAAGGCGCTATCCGCTTTAGAGGATTAAACCACTGGAAAATCGAAACAGTGAGGTAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (27-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-697)

• Competence protein (Competence) (213-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.695	99.865	0.526
comEC/celB	Streptococcus mitis SK321	52.426	99.865	0.524
comEC/celB	Streptococcus pneumoniae TIGR4	51.144	100	0.511
comEC/celB	Streptococcus pneumoniae Rx1	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae D39	50.606	100	0.506
comEC/celB	Streptococcus pneumoniae R6	50.606	100	0.506
comEC	Lactococcus lactis subsp. cremoris KW2	47.914	100	0.479