Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FOC63_RS00780 Genome accession   NZ_CP054015
Coordinates   164964..165674 (-) Length   236 a.a.
NCBI ID   WP_009854646.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 159964..170674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS00765 (FOC63_00765) rnc 161604..162290 (-) 687 WP_009854642.1 ribonuclease III -
  FOC63_RS00770 (FOC63_00770) vicX 162809..163618 (-) 810 WP_009854644.1 MBL fold metallo-hydrolase Regulator
  FOC63_RS00775 (FOC63_00775) vicK 163619..164971 (-) 1353 WP_009854645.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC63_RS00780 (FOC63_00780) vicR 164964..165674 (-) 711 WP_009854646.1 response regulator YycF Regulator
  FOC63_RS00785 (FOC63_00785) - 165979..166743 (+) 765 WP_009854647.1 amino acid ABC transporter ATP-binding protein -
  FOC63_RS00790 (FOC63_00790) - 166754..167566 (+) 813 WP_014620198.1 transporter substrate-binding domain-containing protein -
  FOC63_RS00795 (FOC63_00795) - 167583..168287 (+) 705 WP_009854649.1 amino acid ABC transporter permease -
  FOC63_RS00800 (FOC63_00800) - 168299..168946 (+) 648 WP_009854650.1 amino acid ABC transporter permease -
  FOC63_RS00805 (FOC63_00805) - 169038..169646 (-) 609 WP_009854651.1 TVP38/TMEM64 family protein -
  FOC63_RS00810 (FOC63_00810) - 169894..170196 (-) 303 WP_009854652.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27150.94 Da        Isoelectric Point: 4.6512

>NTDB_id=450119 FOC63_RS00780 WP_009854646.1 164964..165674(-) (vicR) [Streptococcus gallolyticus strain FDAARGOS_755]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAITKFEEEDPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASASNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=450119 FOC63_RS00780 WP_009854646.1 164964..165674(-) (vicR) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGAAAAAAATTCTTATCGTTGATGATGAAAAACCAATTTCGGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACCGTAACGGCTTTTGATGGTCGTGAAGCTATTACAAAGTTTGAGGAAGAAGATCCAGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTGGCTAAAGAAGTTCGCAAGACAAGTCATATTCCAATCATTATGTTGTCTGCT
AAGGATAGCGAGTTTGATAAAGTTATCGGACTTGAAATCGGTGCAGATGACTATGTAACCAAACCATTTTCAAATCGTGA
ATTGTTGGCGCGTGTTAAAGCGCACCTTCGTCGTACAGAAAATATTGAAACAGCAGTTGCTGAAGAAAATGCTTCTGCTT
CAAATTCAGAAATCACAATTGGCGACTTGAAAATCTTACCAGACGCCTTTGTGGCACAAAAACGTGGTGAAGATATCGAA
TTAACACACCGTGAGTTTGAATTGCTTCATCATTTGGCAACACATATGGGACAAGTCATGACCCGTGAATATCTTTTGGA
AACCGTTTGGGGCTATGATTATTTTGGTGATGTGCGTACGGTTGACGTAACCATTCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGCCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGGTACTACATGAAGTCATATGAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

89.831

100

0.898
  micA Streptococcus pneumoniae Cp1015

77.778

99.153

0.771
  covR Streptococcus salivarius strain HSISS4

47.845

98.305

0.47
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

37.288

100

0.373