Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   FOC73_RS06935 Genome accession   NZ_CP053998
Coordinates   1420590..1422746 (+) Length   718 a.a.
NCBI ID   WP_002883725.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1415590..1427746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS06915 (FOC73_06915) - 1416466..1417197 (+) 732 WP_002883746.1 cyclase family protein -
  FOC73_RS09695 - 1417446..1417655 (+) 210 WP_254388426.1 transposase -
  FOC73_RS09740 - 1417674..1417802 (+) 129 WP_002883737.1 hypothetical protein -
  FOC73_RS06925 (FOC73_06925) - 1418568..1419530 (+) 963 WP_002883806.1 thioredoxin family protein -
  FOC73_RS06930 (FOC73_06930) - 1419896..1420117 (+) 222 WP_022495973.1 garvicin Q family class II bacteriocin -
  FOC73_RS06935 (FOC73_06935) comA/nlmT 1420590..1422746 (+) 2157 WP_002883725.1 peptide cleavage/export ABC transporter Regulator
  FOC73_RS06940 (FOC73_06940) - 1422854..1423831 (+) 978 WP_254388427.1 HlyD family efflux transporter periplasmic adaptor subunit -
  FOC73_RS06945 (FOC73_06945) - 1423977..1424528 (-) 552 WP_157747901.1 GHKL domain-containing protein -
  FOC73_RS06950 (FOC73_06950) - 1425182..1425919 (-) 738 WP_002883766.1 LytTR family DNA-binding domain-containing protein -
  FOC73_RS06955 (FOC73_06955) - 1426648..1427460 (-) 813 WP_002883805.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80860.91 Da        Isoelectric Point: 8.5629

>NTDB_id=449963 FOC73_RS06935 WP_002883725.1 1420590..1422746(+) (comA/nlmT) [Streptococcus salivarius strain FDAARGOS_771]
MLRFRKTFVPQVDMMDCGVAALASISRYYGSDYSLAHLRELTKTTKEGTTALGLVQAAKKMGFETRAIQADMSLFEIKDI
SYPFIVHVAKDGRLQHYYVVYKNKKNHLIIGDPDPSVRITRMSKKGFEKEWTGVALFFAPEPSYKPYKDKKNGLLALVPL
IFKQRSLITNIVLASFLVTLINILGSYYLQVILDEYIPNQMQSTLGIISIGLVVTYILQQMMNFAREYLLTVLSQRLTID
VVLSYIRHIFELPMSFFATRQTGEVTSRFSDANSIIDALASTILSVFLDVSILMIVGGVLLLQNRNLFWLVLYSIPIYLI
IVYTFMKPFEKMNHDVMQSNAMVSSAIIEDINGIETIKSLTSEEVRYQKIDSDFVGYLDNSFKLSRLSILQTSIKQGAQL
ILNVLILWTGAQLVMANTISVGQLITFNMLLSYFTTPLENIINLQTKLQSAKVANARLNEVYLVDSEFQTFQENPYQEQL
LKGDITVSDLSYKYGFGRDALSDINLTIKQGEKVSFVGVSGSGKTTIAKLLVNFYKPYKGTISLNGQNIDQLDKRSLRQF
INYLPQQSYVFSGSLLDNLTLGADPSVVQEDILKACDIAEIRQDIEQMPMGFQTELSDGAGLSGGQKQRIALARALLTKS
RVLILDEATSGLDVLTEKKVVDNLLQLTDKTIIFIAHRLSIAQRTHRIFVMDQGRIVESGSHEELLSQAGFYQRLFQS

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=449963 FOC73_RS06935 WP_002883725.1 1420590..1422746(+) (comA/nlmT) [Streptococcus salivarius strain FDAARGOS_771]
ATGTTACGTTTTCGTAAAACTTTTGTGCCTCAGGTTGATATGATGGATTGTGGTGTGGCAGCTCTTGCTTCTATCTCTAG
GTATTATGGATCAGACTACTCCTTGGCTCATTTGAGAGAATTAACCAAAACAACCAAGGAGGGCACAACAGCCCTTGGTT
TAGTTCAGGCGGCTAAAAAAATGGGGTTTGAAACAAGGGCTATTCAAGCGGATATGTCTCTCTTTGAGATTAAAGATATA
TCCTATCCTTTTATCGTTCATGTCGCAAAAGATGGTAGACTACAACATTATTATGTGGTCTATAAAAATAAGAAAAATCA
TCTCATTATTGGAGATCCGGACCCTAGCGTCAGAATAACTAGGATGTCCAAAAAGGGGTTTGAAAAGGAGTGGACAGGTG
TCGCCTTATTTTTTGCACCAGAACCCAGCTATAAACCATACAAGGATAAGAAAAATGGTTTATTAGCTCTTGTTCCACTT
ATTTTCAAGCAAAGATCTCTTATCACCAATATTGTCTTAGCTAGTTTTTTAGTTACTTTGATCAATATATTAGGTTCTTA
TTACTTGCAGGTAATTTTGGATGAGTATATCCCGAATCAGATGCAGTCAACTTTGGGAATTATTTCAATTGGTTTGGTTG
TGACCTACATTTTGCAACAAATGATGAATTTTGCCAGGGAGTACTTACTGACTGTGCTGAGTCAACGTCTAACTATTGAT
GTGGTCTTATCCTATATTCGGCATATTTTTGAACTTCCCATGTCCTTTTTTGCGACGCGACAGACGGGAGAGGTAACTTC
ACGTTTTAGTGATGCCAATTCGATTATTGATGCGTTAGCATCGACCATCTTATCTGTTTTCTTAGATGTTTCAATTTTGA
TGATTGTGGGTGGTGTCCTTCTTCTCCAAAATAGGAATCTATTTTGGTTAGTCTTGTACTCCATACCGATTTATTTGATT
ATTGTCTATACCTTTATGAAGCCCTTTGAAAAGATGAACCATGATGTTATGCAAAGCAATGCTATGGTGAGCTCAGCGAT
AATTGAGGATATCAATGGGATTGAGACCATTAAATCTCTAACTAGTGAAGAGGTCCGTTATCAAAAGATTGATAGTGACT
TTGTAGGTTATTTGGATAACTCCTTTAAGTTGTCCAGATTATCTATCTTACAGACCTCTATAAAACAAGGGGCACAATTG
ATTTTAAATGTGCTCATTCTATGGACAGGAGCTCAGCTCGTTATGGCAAATACGATATCAGTTGGTCAGTTGATTACGTT
TAACATGCTCTTGTCCTATTTCACAACACCATTAGAAAATATCATCAATCTCCAAACCAAACTTCAGTCTGCAAAGGTGG
CCAATGCCCGTTTAAACGAGGTATATCTAGTGGATTCAGAGTTTCAAACGTTCCAAGAAAATCCATATCAAGAACAGCTA
CTTAAAGGTGATATCACTGTCTCTGACCTATCTTATAAATATGGTTTTGGTCGAGATGCTTTATCAGATATCAATCTAAC
TATCAAACAAGGAGAAAAAGTTAGTTTTGTGGGTGTTAGTGGGTCTGGTAAGACAACCATAGCCAAGCTCTTAGTAAACT
TTTATAAGCCTTACAAAGGTACGATTAGTTTAAATGGTCAAAATATCGATCAGTTGGATAAGAGATCCTTACGTCAGTTT
ATCAACTATCTTCCCCAACAGTCTTATGTTTTTAGTGGTAGTCTATTAGACAACCTAACTTTGGGAGCTGATCCTAGCGT
GGTGCAGGAGGATATTTTAAAAGCTTGCGATATAGCAGAGATACGTCAAGATATTGAACAAATGCCCATGGGATTTCAAA
CAGAACTTTCAGATGGAGCGGGTCTTTCAGGAGGACAAAAGCAGAGGATTGCTTTGGCTCGTGCCCTCCTAACGAAATCT
CGAGTGCTTATCTTAGATGAAGCGACGAGTGGATTGGATGTATTAACAGAGAAAAAAGTCGTTGATAACTTATTGCAACT
AACAGATAAGACGATAATTTTTATAGCCCATCGTTTGAGTATCGCTCAGCGAACACATCGTATTTTTGTTATGGATCAAG
GTCGCATAGTTGAGAGTGGTTCTCATGAGGAATTGTTGTCTCAAGCAGGCTTTTACCAGCGTCTCTTTCAAAGTTAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(501-650)

ABC transporter transmembrane region (ABC_membrane)

(169-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

68.106

100

0.681
  comA Streptococcus mitis NCTC 12261

65.175

99.582

0.649
  comA Streptococcus pneumoniae D39

64.615

99.582

0.643
  comA Streptococcus pneumoniae R6

64.615

99.582

0.643
  comA Streptococcus pneumoniae Rx1

64.615

99.582

0.643
  comA Streptococcus mitis SK321

64.476

99.582

0.642
  comA Streptococcus gordonii str. Challis substr. CH1

63.448

100

0.641
  comA Streptococcus pneumoniae TIGR4

64.196

99.582

0.639