Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   FOC73_RS02535 Genome accession   NZ_CP053998
Coordinates   566860..568734 (-) Length   624 a.a.
NCBI ID   WP_002884755.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 561860..573734
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS02500 (FOC73_02500) rimM 562238..562756 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  FOC73_RS02515 (FOC73_02515) - 563453..564097 (-) 645 WP_002884791.1 response regulator transcription factor -
  FOC73_RS02520 (FOC73_02520) - 564087..565097 (-) 1011 WP_002884643.1 sensor histidine kinase -
  FOC73_RS02525 (FOC73_02525) liaF 565094..565792 (-) 699 WP_002884385.1 cell wall-active antibiotics response protein LiaF -
  FOC73_RS02530 (FOC73_02530) - 565956..566714 (-) 759 WP_002884314.1 potassium channel family protein -
  FOC73_RS02535 (FOC73_02535) stkP/pknB 566860..568734 (-) 1875 WP_002884755.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FOC73_RS02540 (FOC73_02540) - 568734..569471 (-) 738 WP_037604753.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FOC73_RS02545 (FOC73_02545) rsmB 569515..570837 (-) 1323 WP_002884194.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  FOC73_RS02550 (FOC73_02550) fmt 570827..571762 (-) 936 WP_002884812.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67925.61 Da        Isoelectric Point: 6.5786

>NTDB_id=449922 FOC73_RS02535 WP_002884755.1 566860..568734(-) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_771]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNERVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSAAQTNIEGAGFKVGDVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGVKLDKDKIPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=449922 FOC73_RS02535 WP_002884755.1 566860..568734(-) (stkP/pknB) [Streptococcus salivarius strain FDAARGOS_771]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAGTCTATCGGGCGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGAGTAGCTATTAAGGTGCTACGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTTTTGGTGATGGAGTATGTAGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACTAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
GAAAGCAACTATCCAAAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGACAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCTATTTTGGCAGAGAACCGTAATGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAACTAGAGAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCTGCAAGTCTTGAGAAAAAAGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCGAGGAAGAAAACGACACCAGCTAAGAAGAAAAAGAAGAAAAACTTTTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCGCAGCTCAGACTAACATTGAGGGTGCTGGATTTAAGGTAGGAGACGTTAAGGAAGTG
GAAGATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACTACACGAAAAGAAGGATCAAGTAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGATCAAATTGATATTCAGCATGTCGAAGACGATAATGCTGAAGAGGGAGAA
ATCTTATCTCAAAGTCCAGGAAAAAACAAGTCCTTCAACCCTAAGGATAGTAAGGCTAAAATCAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGTATCGAGTATCATGACTATAATACTGGTGTTAAGTTAGACAAGGATAAGATTCCTAGCAGTACAGAGGTC
CTATATCAAGATCCACAAGCTGGTACAAGCGTTGATGGTACAGTGATCCTCTATGTTTCAGTTGCAACAGCAAGTTCAAG
TCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(511-580)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.237

100

0.982
  pknB Streptococcus mutans UA159

67.159

86.859

0.583
  stkP Streptococcus pneumoniae TIGR4

51.979

93.109

0.484
  stkP Streptococcus pneumoniae D39

51.807

93.109

0.482
  stkP Streptococcus pneumoniae R6

51.807

93.109

0.482
  stkP Streptococcus pneumoniae Rx1

51.635

93.109

0.481