Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   STCNRZ1202_RS07775 Genome accession   NZ_CP065506
Coordinates   1489571..1490938 (-) Length   455 a.a.
NCBI ID   WP_347229602.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ1202     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1484571..1495938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1202_RS07745 (STCNRZ1202_07755) - 1484988..1485230 (-) 243 WP_096811635.1 Blp family class II bacteriocin -
  STCNRZ1202_RS07750 - 1485481..1485882 (-) 402 WP_011226490.1 hypothetical protein -
  STCNRZ1202_RS07755 (STCNRZ1202_07760) - 1486850..1487056 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  STCNRZ1202_RS07760 (STCNRZ1202_07765) comE/blpR 1487306..1488037 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  STCNRZ1202_RS07765 comD/blpH 1488574..1489377 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  STCNRZ1202_RS07770 (STCNRZ1202_07775) - 1489395..1489556 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STCNRZ1202_RS07775 (STCNRZ1202_07780) comB 1489571..1490938 (-) 1368 WP_347229602.1 bacteriocin secretion accessory protein Regulator
  STCNRZ1202_RS07780 (STCNRZ1202_07785) comA/nlmT 1490954..1493122 (-) 2169 WP_347229603.1 peptide cleavage/export ABC transporter Regulator
  STCNRZ1202_RS07785 (STCNRZ1202_07790) - 1494121..1495866 (-) 1746 WP_347229604.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50429.19 Da        Isoelectric Point: 4.7492

>NTDB_id=449809 STCNRZ1202_RS07775 WP_347229602.1 1489571..1490938(-) (comB) [Streptococcus thermophilus strain CNRZ1202]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKIIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGMAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSIIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=449809 STCNRZ1202_RS07775 WP_347229602.1 1489571..1490938(-) (comB) [Streptococcus thermophilus strain CNRZ1202]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGATTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTATGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAATCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCATTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.911

99.121

0.396
  comB Streptococcus pneumoniae D39

39.911

99.121

0.396
  comB Streptococcus pneumoniae R6

39.911

99.121

0.396
  comB Streptococcus pneumoniae TIGR4

39.246

99.121

0.389
  comB Streptococcus mitis SK321

38.581

99.121

0.382
  comB Streptococcus mitis NCTC 12261

38.581

99.121

0.382