Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GGS_RS10415 Genome accession   NC_018712
Coordinates   2149048..2150271 (+) Length   407 a.a.
NCBI ID   WP_003054444.1    Uniprot ID   A0ABU0A9Q0
Organism   Streptococcus dysgalactiae subsp. equisimilis RE378     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2144048..2155271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GGS_RS10400 (GGS_1974) - 2147114..2148133 (+) 1020 WP_015017523.1 IS30 family transposase -
  GGS_RS10410 (GGS_1976) rlmH 2148356..2148835 (-) 480 WP_003057960.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GGS_RS10415 (GGS_1977) htrA 2149048..2150271 (+) 1224 WP_003054444.1 trypsin-like peptidase domain-containing protein Regulator
  GGS_RS10420 (GGS_1978) spo0J 2150360..2151136 (+) 777 WP_003054458.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 42746.35 Da        Isoelectric Point: 7.3920

>NTDB_id=44953 GGS_RS10415 WP_003054444.1 2149048..2150271(+) (htrA) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MPSMKHILKSLSVLLIGFLGGLIAIITFNNLYPHSPSKINSGKATTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSS
SLSNPYTKLFGEGRSKENKDAELSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGIGFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQ
INIPTSVTGGIVVAEVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKADIKLTKTT
QDLTKTQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=44953 GGS_RS10415 WP_003054444.1 2149048..2150271(+) (htrA) [Streptococcus dysgalactiae subsp. equisimilis RE378]
ATGCCAAGTATGAAACATATCTTAAAATCCTTAAGTGTTTTACTAATTGGATTTTTAGGAGGATTAATAGCAATTATTAC
ATTTAATAATCTCTACCCACATTCTCCTTCAAAAATAAATTCAGGTAAGGCAACAACTAGTAATATGGTTTTTAACAACA
CAACCAATACTACTAAAGCTGTCAAAGCTGTTCAAAATGCAGTTGTATCAGTTATTAATTATCAAGATAACCCTTCTTCA
TCCCTTTCTAACCCTTATACAAAACTCTTTGGAGAAGGGCGTTCAAAAGAGAATAAGGATGCTGAATTATCTATTTTTAG
TGAAGGATCTGGGGTCATTTATCGAAAAGATGGCAACTCCGCTTACGTTGTTACTAATAACCATGTTATCGACGGAGCTA
AACGGATTGAAATTCTTATGGCAGACGGATCTAAAGTTGTTGGTGAATTAGTTGGAGCTGATACTTATTCGGATTTAGCT
GTTGTTAAGATCTCTTCAGATAAGATAAAAACAGTAGCTGAATTTGCAGACTCTACAAAACTAAATGTTGGAGAAGTTGC
TATTGCTATCGGCAGCCCACTAGGAACACAATACGCTAATTCTGTTACTCAAGGAATCGTCTCTAGTTTAAGTCGTACTG
TAACTTTAAAAAACGAGAATGGTGAGACTGTCTCAACAAATGCTATTCAGACAGATGCTGCTATTAATCCTGGAAACTCT
GGTGGACCACTAATTAATATTGAGGGGCAAGTAATCGGAATTAATTCAAGTAAAATTTCTTCTACCCCAACTGGTAGCAA
CGGTAATAGTGGTGCTGTTGAAGGAATTGGTTTTGCTATCCCATCTACTGACGTTATTAAAATTATTAAACAACTAGAAA
CTAATGGTGAAGTTATCAGACCTGCTCTTGGAATATCCATGGTCAATTTAAATGACTTATCCACAAATGCTCTTAGCCAA
ATTAATATTCCAACTAGTGTAACTGGTGGTATTGTAGTAGCAGAAGTTAAGGAAGGAATGCCGGCATCTGGCAAACTTGC
TCAGTACGATGTGATTACAGAAATTGATGGCAAAACAGTTAATTCAATTAGTGATTTACAAAGTAGTCTATACGGACACG
ATATTAATGATACTATTAAAGTAACTTTTTATAGAGGAACTACAAAGAAAAAAGCAGATATCAAATTAACAAAAACTACT
CAAGATTTGACTAAAACGCAGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(109-254)

PDZ domain (PDZ_2)

(301-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.634

99.263

0.612
  htrA Streptococcus gordonii str. Challis substr. CH1

55.473

98.771

0.548
  htrA Streptococcus mitis NCTC 12261

53.317

100

0.533
  htrA Streptococcus pneumoniae Rx1

53.071

100

0.531
  htrA Streptococcus pneumoniae D39

53.071

100

0.531
  htrA Streptococcus pneumoniae R6

53.071

100

0.531
  htrA Streptococcus pneumoniae TIGR4

53.071

100

0.531