Detailed information NTG0449273

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ST4067_RS07155
• Genome accession: NZ_CP065496
• Coordinates: 1374207..1376447 (-)
• Length: 746 a.a.
• NCBI ID: WP_263604460.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4067
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1369207..1381447

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4067_RS07135 (ST4067_07165)	-	1370071..1370931 (-)	861	WP_011227466.1	methionyl aminopeptidase	-
ST4067_RS07140 (ST4067_07170)	spxR	1370975..1372255 (-)	1281	WP_096811595.1	CBS-HotDog domain-containing transcription factor SpxR	-
ST4067_RS07145 (ST4067_07175)	-	1372248..1372793 (-)	546	WP_022096992.1	GNAT family N-acetyltransferase	-
ST4067_RS07150 (ST4067_07180)	-	1372859..1374121 (-)	1263	WP_022096991.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4067_RS07155 (ST4067_07185)	comEC/celB	1374207..1376447 (-)	2241	WP_263604460.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ST4067_RS07160 (ST4067_07190)	comEA	1376437..1377132 (-)	696	WP_082309090.1	helix-hairpin-helix domain-containing protein	Machinery gene
ST4067_RS07165 (ST4067_07195)	-	1377241..1377996 (-)	756	WP_002948862.1	lysophospholipid acyltransferase family protein	-
ST4067_RS09730	-	1378194..1378739 (+)	546	WP_263604461.1	polysaccharide deacetylase family protein	-
ST4067_RS07175	-	1378655..1379071 (+)	417	WP_311316677.1	hypothetical protein	-
ST4067_RS07180 (ST4067_07205)	-	1379121..1379885 (+)	765	WP_084826100.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ST4067_RS07185 (ST4067_07210)	-	1379889..1380158 (+)	270	WP_002948849.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84873.77 Da
• Isoelectric Point: 9.8464

>NTDB_id=449273 ST4067_RS07155 WP_263604460.1 1374207..1376447(-) (comEC/celB) [Streptococcus thermophilus strain 4067]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TSAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYQLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKDSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=449273 ST4067_RS07155 WP_263604460.1 1374207..1376447(-) (comEC/celB) [Streptococcus thermophilus strain 4067]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACCTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTTCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCAGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGATTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTGAGTTGTTCTTACGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGACTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTCTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.721	100	0.477
comEC/celB	Streptococcus mitis SK321	46.988	100	0.471
comEC/celB	Streptococcus pneumoniae TIGR4	45.917	100	0.46
comEC/celB	Streptococcus pneumoniae D39	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae Rx1	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae R6	45.649	100	0.457
comEC	Lactococcus lactis subsp. cremoris KW2	45.103	97.185	0.438