Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   FOC66_RS10135 Genome accession   NZ_CP053939
Coordinates   2110021..2110908 (-) Length   295 a.a.
NCBI ID   WP_003748312.1    Uniprot ID   -
Organism   Neisseria mucosa strain FDAARGOS_758     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2105021..2115908
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC66_RS10105 (FOC66_10105) ftsZ 2105284..2106483 (+) 1200 WP_003748303.1 cell division protein FtsZ -
  FOC66_RS10110 (FOC66_10110) ispH 2106604..2107572 (-) 969 WP_003748306.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  FOC66_RS10115 (FOC66_10115) lspA 2107586..2108092 (-) 507 WP_003748308.1 signal peptidase II -
  FOC66_RS10120 (FOC66_10120) glyQ 2108241..2109140 (-) 900 WP_003685919.1 glycine--tRNA ligase subunit alpha -
  FOC66_RS10125 (FOC66_10125) yacG 2109222..2109404 (-) 183 WP_003682475.1 DNA gyrase inhibitor YacG -
  FOC66_RS10130 (FOC66_10130) coaE 2109401..2110021 (-) 621 WP_003748310.1 dephospho-CoA kinase -
  FOC66_RS10135 (FOC66_10135) pilD 2110021..2110908 (-) 888 WP_003748312.1 A24 family peptidase Machinery gene
  FOC66_RS10140 (FOC66_10140) pilG 2110910..2112151 (-) 1242 WP_003748314.1 type II secretion system F family protein Machinery gene
  FOC66_RS10145 (FOC66_10145) pilF 2112231..2113910 (-) 1680 WP_003748316.1 type IV-A pilus assembly ATPase PilB Machinery gene

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 32438.67 Da        Isoelectric Point: 8.3206

>NTDB_id=449274 FOC66_RS10135 WP_003748312.1 2110021..2110908(-) (pilD) [Neisseria mucosa strain FDAARGOS_758]
MLDSIYSAIDALSVLAPFVIPLAVILGLLIGSFLNVVIYRTPIMMEREWTQFSKEHLGIELADEEKQPFNLRKPDSRCPK
CKSPIRVWQNIPILSYVFLGGKCHACKTHISIRYPLIELLTGVLFGIVTWQYGWSWATIGGLILTAILIALTFIDADTQY
LPDSLTQPLIWIGLLFNLNDTFVPLHSAVWGAIAGYMSLYTLCAVYKLLTGKIGMGNGDFKLLAALGAWLGVGILPVLIF
MAALVGLLGALIARVGKGQYFAFGPSLAVAGWIILVANAPITQLVQWWLVQSGFR

Nucleotide


Download         Length: 888 bp        

>NTDB_id=449274 FOC66_RS10135 WP_003748312.1 2110021..2110908(-) (pilD) [Neisseria mucosa strain FDAARGOS_758]
ATGCTTGATAGTATTTACTCTGCCATCGACGCCCTCTCCGTTCTTGCGCCATTCGTTATTCCTTTAGCCGTTATTTTGGG
ATTACTGATTGGTAGCTTTCTGAATGTCGTCATTTATCGCACGCCGATAATGATGGAGCGTGAATGGACACAATTTTCCA
AAGAGCATTTGGGCATCGAGCTGGCAGACGAAGAAAAACAGCCATTTAATCTGCGTAAACCGGATTCACGCTGCCCAAAA
TGCAAAAGTCCGATCAGAGTTTGGCAAAATATACCCATCCTCAGCTATGTTTTCCTAGGTGGGAAATGCCACGCCTGCAA
AACCCATATCAGCATACGCTATCCGTTGATTGAGCTGCTGACAGGTGTCTTATTCGGTATTGTCACGTGGCAATACGGCT
GGTCATGGGCAACTATTGGCGGATTGATTCTGACTGCTATATTGATTGCGCTGACCTTTATCGATGCCGATACGCAATAT
TTGCCCGACAGCCTGACTCAGCCCCTAATTTGGATCGGCCTGCTGTTTAATCTGAACGATACATTCGTGCCCCTGCATTC
AGCCGTTTGGGGCGCGATTGCAGGCTATATGAGCCTTTATACTTTATGCGCCGTCTATAAACTTCTGACCGGTAAAATCG
GCATGGGCAATGGCGATTTCAAACTTTTGGCCGCACTCGGTGCATGGCTGGGCGTAGGAATTTTGCCTGTTCTGATCTTC
ATGGCTGCCTTAGTCGGGCTGTTAGGCGCACTCATCGCCCGCGTCGGTAAAGGTCAGTATTTTGCTTTTGGTCCCAGCCT
TGCTGTAGCAGGATGGATTATTTTGGTTGCCAATGCACCTATTACCCAACTGGTACAATGGTGGCTCGTACAATCAGGAT
TCCGATAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(142-248)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(25-132)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

69.965

95.932

0.671
  pilD Vibrio cholerae strain A1552

47.368

90.169

0.427
  pilD Vibrio campbellii strain DS40M4

44.727

93.22

0.417
  pilD Acinetobacter baumannii D1279779

47.41

85.085

0.403
  pilD Acinetobacter nosocomialis M2

47.41

85.085

0.403