Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GE021_RS02010 Genome accession   NZ_CP053792
Coordinates   393786..394547 (+) Length   253 a.a.
NCBI ID   WP_125074782.1    Uniprot ID   A0A3P5Y8F8
Organism   Streptococcus canis strain HL_77_1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 388786..399547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS01995 (GE021_001995) - 390516..390919 (+) 404 Protein_359 DUF2207 domain-containing protein -
  GE021_RS02000 (GE021_002000) - 391372..392529 (-) 1158 WP_172774156.1 IS110 family transposase -
  GE021_RS02005 (GE021_002005) - 392804..393643 (+) 840 WP_125074781.1 undecaprenyl-diphosphate phosphatase -
  GE021_RS02010 (GE021_002010) mecA 393786..394547 (+) 762 WP_125074782.1 adaptor protein MecA Regulator
  GE021_RS02015 (GE021_002015) - 394554..395723 (+) 1170 WP_125074783.1 glycosyltransferase family 4 protein -
  GE021_RS02020 (GE021_002020) sufC 395847..396617 (+) 771 WP_003046647.1 Fe-S cluster assembly ATPase SufC -
  GE021_RS02025 (GE021_002025) sufD 396716..397978 (+) 1263 WP_125074784.1 Fe-S cluster assembly protein SufD -
  GE021_RS02030 (GE021_002030) - 398009..399235 (+) 1227 WP_125074785.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29166.84 Da        Isoelectric Point: 4.1037

>NTDB_id=447256 GE021_RS02010 WP_125074782.1 393786..394547(+) (mecA) [Streptococcus canis strain HL_77_1]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKELNFEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEIMEDVVEATLTGQAEATDETHEVDTEPLDYVH
YVLDFATLPEAITFAKTIDFSIEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEYATPGSKTRAYLQEHGLQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=447256 GE021_RS02010 WP_125074782.1 393786..394547(+) (mecA) [Streptococcus canis strain HL_77_1]
ATGGAAATGAAACAAATTAGCGAGACAACGCTGAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGAATGGAGCT
AAAAGATTTTCTCATTCCCCAAGAAAAAACGGAAGAGTTCTTTTATTCTGTTATGGATGAACTAGATCTTCCAGATAATT
TTAAAGATAGTGGCATGCTTAGTTTTCGAGTAACGCCAAGAAAAGACCGGCTAGATGTTTTTGTAACCAAATCTGAGCTT
AATAAGGAGCTCAACTTTGAAGATTTGGCAGATTTGGGTGATATTTCTCAAATGACACCTGAAGATTTTTTCAAAAGTTT
GGAGCAATCCATGCGTGAAAAAGGGGATGTCAATGCGCATGAGAAATTGGAAAAAATTGAAGAAATCATGGAAGACGTGG
TCGAAGCAACCTTAACTGGTCAGGCTGAGGCAACAGATGAAACGCATGAGGTCGATACAGAACCATTGGATTATGTGCAC
TATGTTTTGGACTTTGCTACCCTTCCAGAGGCGATAACCTTCGCCAAAACCATTGATTTCTCTATTGAAGCTTCAGAATT
ATACAAGGGTGACAGCCGTTACCACATGACCATTTTATTGGACGTTCAACAGCAGCCGTCATATTTTGCGAATGTTATGT
ATGCAAGGTTAATTGAGTATGCAACCCCTGGGTCAAAAACAAGAGCCTACTTGCAAGAGCATGGCTTACAATTGATTCTA
GATGGCGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5Y8F8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

56.627

98.419

0.557
  mecA Streptococcus thermophilus LMG 18311

56.225

98.419

0.553
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.486
  mecA Streptococcus pneumoniae Rx1

48.221

100

0.482
  mecA Streptococcus pneumoniae D39

48.221

100

0.482
  mecA Streptococcus pneumoniae R6

48.221

100

0.482