Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   GE022_RS07865 Genome accession   NZ_CP053790
Coordinates   1603809..1605704 (-) Length   631 a.a.
NCBI ID   WP_164405061.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1598809..1610704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS07840 (GE022_007830) - 1599559..1599918 (-) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  GE022_RS07845 (GE022_007835) - 1599918..1601318 (-) 1401 WP_164405059.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GE022_RS07850 (GE022_007840) - 1601355..1601996 (-) 642 WP_003044709.1 response regulator transcription factor -
  GE022_RS07855 (GE022_007845) - 1601989..1602993 (-) 1005 WP_164405060.1 sensor histidine kinase -
  GE022_RS07860 (GE022_007850) liaF 1602990..1603682 (-) 693 WP_003044714.1 cell wall-active antibiotics response protein LiaF -
  GE022_RS07865 (GE022_007855) pknB 1603809..1605704 (-) 1896 WP_164405061.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GE022_RS07870 (GE022_007860) - 1605701..1606441 (-) 741 WP_003044720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GE022_RS07875 (GE022_007865) rsmB 1606479..1607801 (-) 1323 WP_164405062.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GE022_RS07880 (GE022_007870) fmt 1607791..1608726 (-) 936 WP_164405063.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68783.09 Da        Isoelectric Point: 6.9928

>NTDB_id=447229 GE022_RS07865 WP_164405061.1 1603809..1605704(-) (pknB) [Streptococcus canis strain HL_77_2]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKNGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENHNVP
QALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKVIFDDVESTKPLPKVTPTPMTTPKVAPTPVTSTTESRL
EQTNQMDTLQKPQKKKRNGRFLGTLLKILFSLFIVGVALFTYLVLTKPTSVKVPDVTGASLKVAKQELQDLGLKVGKVRQ
IESDTVAEGNVVRTDPQAGTAKRKGSSVTVYLSIGNKGFEMENYKGVDYQDAMNSLMETYGIPKSKIKIERIVTNEYPEN
TVISQSPSAGDKFNPNGKSKITLSVAVSDTVIMPMVTEYSYADAVNTLTALGIDASRIKAYAPSSSSATGFIQVNSPSSK
AIVSGQMPYYGTTLSLSEKGEISLYLYPEETHSSSGSSSSESSSSSSSTSDGTGTSSNTELNPSESTGQTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=447229 GE022_RS07865 WP_164405061.1 1603809..1605704(-) (pknB) [Streptococcus canis strain HL_77_2]
ATGATTCAGATTGGCAAGTTATTTGCTGGTCGTTATCGTATTCTAAAATCTATTGGCCGCGGTGGTATGGCGGATGTTTA
TTTGGCAAATGATTTGATCTTGGATAATGAAGACGTTGCAATCAAAGTTTTGCGTACCAATTATCAAACAGATCAGGTGG
CAGTTGCGCGTTTCCAACGGGAAGCGCGGGCCATGGCTGAATTGAACCATCCGAATATTGTTGCCATCCGGGATATAGGT
GAAGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGTGCTGACCTAAAGAAGTACATTCAAGATCATGCACC
GCTATCTAATAACGAAGTGGTTAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCTCACCAAAAAGGAATTGTGC
ATAGGGATTTAAAACCTCAAAACATTCTCTTAACTAAAAATGGTGTGGTTAAGGTGACTGACTTTGGGATTGCTGTTGCC
TTTGCAGAAACGAGTTTGACTCAGACCAACTCGATGTTAGGTAGTGTGCATTATTTGTCTCCGGAGCAGGCTCGTGGTTC
AAAGGCAACTATCCAAAGTGACATTTATGCAATGGGGATTATGCTCTTTGAAATGCTGACAGGGCATATTCCTTATGACG
GTGACAGTGCTGTTACGATTGCCTTGCAACATTTCCAAAAGCCTCTTCCGTCTATTATTGACGAAAATCACAATGTGCCG
CAAGCTTTAGAGAATGTTGTTATCCGAGCAACAGCCAAGAAATTGAGTGATCGTTATGGGTCCACTTTTGAGATGAGCCG
TGACTTGATGACGGCGCTTAGCTACAACCGTAGCCGTGAACGTAAAGTCATTTTTGATGATGTGGAAAGCACTAAGCCGC
TTCCCAAAGTAACCCCAACGCCAATGACAACACCAAAAGTTGCGCCGACTCCAGTTACTTCAACAACTGAAAGTAGATTA
GAGCAAACCAATCAAATGGACACGCTCCAAAAGCCACAAAAAAAGAAAAGAAATGGTCGTTTTTTAGGAACCTTATTGAA
GATTCTTTTTTCTCTCTTTATTGTGGGGGTGGCTCTTTTTACTTACTTGGTATTAACTAAGCCAACTTCTGTGAAAGTTC
CTGATGTAACAGGTGCTAGCTTGAAAGTAGCTAAGCAAGAACTACAAGATCTTGGTCTAAAAGTAGGAAAGGTACGGCAA
ATTGAAAGCGATACTGTCGCTGAAGGAAATGTTGTCCGAACAGACCCACAAGCAGGAACAGCTAAGCGTAAAGGATCAAG
TGTAACTGTTTATTTGTCAATCGGAAATAAAGGTTTTGAAATGGAAAACTACAAAGGGGTTGATTATCAAGATGCTATGA
ACAGCTTGATGGAAACCTATGGCATTCCAAAATCTAAGATTAAAATTGAACGTATTGTGACCAATGAGTATCCTGAAAAT
ACTGTTATTAGCCAGTCACCAAGTGCAGGAGATAAGTTTAACCCCAATGGTAAATCTAAAATTACCCTTAGCGTAGCCGT
TAGTGACACAGTCATTATGCCAATGGTTACAGAATATAGTTATGCTGATGCGGTTAATACTTTGACAGCACTGGGTATTG
ATGCCTCTAGGATAAAAGCTTATGCGCCAAGTTCAAGTTCAGCAACTGGTTTTATTCAGGTTAATTCCCCTAGTTCAAAA
GCTATTGTTAGTGGACAGATGCCTTATTATGGTACGACATTGAGTCTTTCTGAAAAAGGAGAGATAAGCCTTTATCTTTA
TCCAGAAGAAACACACTCTTCAAGTGGTTCCTCAAGTTCAGAATCAAGTTCAAGTAGCTCCTCAACAAGTGATGGCACTG
GGACAAGTAGCAATACCGAATTAAACCCGTCAGAATCGACTGGACAAACACCTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(371-433)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.529

92.868

0.609
  stkP/pknB Streptococcus salivarius strain HSISS4

62.203

93.502

0.582
  stkP Streptococcus pneumoniae TIGR4

58.221

81.933

0.477
  stkP Streptococcus pneumoniae D39

57.803

82.25

0.475
  stkP Streptococcus pneumoniae R6

57.803

82.25

0.475
  stkP Streptococcus pneumoniae Rx1

57.834

81.933

0.474