Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GE022_RS01825 Genome accession   NZ_CP053790
Coordinates   345816..346577 (+) Length   253 a.a.
NCBI ID   WP_164405046.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 340816..351577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS01800 (GE022_001800) - 340866..341756 (+) 891 WP_003046627.1 SPFH domain-containing protein -
  GE022_RS01805 (GE022_001805) - 341895..342011 (-) 117 WP_003046630.1 putative metal homeostasis protein -
  GE022_RS01810 (GE022_001810) - 342154..342894 (-) 741 WP_003046632.1 amino acid ABC transporter ATP-binding protein -
  GE022_RS01815 (GE022_001815) - 342887..344455 (-) 1569 WP_164405045.1 ABC transporter substrate-binding protein/permease -
  GE022_RS01820 (GE022_001820) - 344833..345672 (+) 840 WP_003046638.1 undecaprenyl-diphosphate phosphatase -
  GE022_RS01825 (GE022_001825) mecA 345816..346577 (+) 762 WP_164405046.1 adaptor protein MecA Regulator
  GE022_RS01830 (GE022_001830) - 346584..347753 (+) 1170 WP_093999420.1 glycosyltransferase family 4 protein -
  GE022_RS01835 (GE022_001835) sufC 347877..348647 (+) 771 WP_003046647.1 Fe-S cluster assembly ATPase SufC -
  GE022_RS01840 (GE022_001840) sufD 348746..350008 (+) 1263 WP_003046650.1 Fe-S cluster assembly protein SufD -
  GE022_RS01845 (GE022_001845) - 350039..351265 (+) 1227 WP_003046653.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29262.97 Da        Isoelectric Point: 4.0845

>NTDB_id=447201 GE022_RS01825 WP_164405046.1 345816..346577(+) (mecA) [Streptococcus canis strain HL_77_2]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKELNFEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEIMEDVVEATLTGQAETTDETHEVDLEPLDYVH
YVLDFDTLPEAITFAKTIDFPIEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEYATPGSKTRAYLQEHGLQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=447201 GE022_RS01825 WP_164405046.1 345816..346577(+) (mecA) [Streptococcus canis strain HL_77_2]
ATGGAAATGAAACAAATTAGCGAGACAACGCTGAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGAATGGAGTT
AAAAGATTTTCTCATTCCCCAAGAAAAAACGGAAGAGTTCTTTTATTCTGTTATGGATGAACTAGATCTTCCAGATAATT
TTAAAGATAGTGGCATGCTTAGTTTTCGAGTAACACCAAGAAAAGATCGACTAGATGTTTTTGTAACCAAATCTGAGCTT
AATAAGGAGCTTAACTTTGAAGATTTGGCGGATTTGGGTGATATTTCTCAAATGACACCTGAAGATTTTTTCAAAAGTTT
GGAGCAATCCATGCGTGAAAAAGGGGATGTCAATGCGCATGAGAAATTGGAAAAAATTGAAGAAATCATGGAAGACGTGG
TCGAAGCAACCTTAACTGGTCAGGCTGAGACAACAGATGAAACGCATGAGGTCGATCTAGAACCATTGGATTATGTGCAC
TATGTTTTGGACTTTGATACCCTTCCAGAGGCGATAACCTTCGCCAAAACCATTGATTTCCCTATTGAAGCTTCAGAATT
ATACAAGGGTGACAGCCGTTACCACATGACCATTTTATTGGATGTTCAACAGCAGCCGTCATATTTTGCGAATGTTATGT
ATGCAAGGTTAATTGAGTATGCAACCCCTGGGTCAAAAACAAGAGCCTACTTGCAAGAGCATGGCTTACAATTGATTCTA
GATGGCGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64

98.814

0.632
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.823

98.419

0.549
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.482
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.478
  mecA Streptococcus pneumoniae D39

47.826

100

0.478
  mecA Streptococcus pneumoniae R6

47.826

100

0.478