Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GE022_RS00370 Genome accession   NZ_CP053790
Coordinates   56888..57799 (+) Length   303 a.a.
NCBI ID   WP_003046007.1    Uniprot ID   A0AAE4Q9F2
Organism   Streptococcus canis strain HL_77_2     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 51888..62799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS00355 (GE022_000355) purE 53392..53883 (+) 492 WP_003046002.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  GE022_RS00360 (GE022_000360) purK 53870..54940 (+) 1071 WP_164405430.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  GE022_RS00365 (GE022_000365) purB 55459..56751 (+) 1293 WP_164228814.1 adenylosuccinate lyase -
  GE022_RS00370 (GE022_000370) comR 56888..57799 (+) 912 WP_003046007.1 helix-turn-helix domain-containing protein Regulator
  GE022_RS10520 comS 57886..57987 (+) 102 WP_217267493.1 quorum-sensing system DWW-type pheromone Regulator
  GE022_RS00375 (GE022_000375) ruvB 58020..59018 (+) 999 WP_164405431.1 Holliday junction branch migration DNA helicase RuvB -
  GE022_RS00380 (GE022_000380) - 59159..59602 (+) 444 WP_093999215.1 low molecular weight protein-tyrosine-phosphatase -
  GE022_RS00385 (GE022_000385) - 59619..60020 (+) 402 WP_003046016.1 MORN repeat-containing protein -
  GE022_RS00390 (GE022_000390) - 60017..61792 (+) 1776 WP_164405432.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 36092.66 Da        Isoelectric Point: 5.0503

>NTDB_id=447190 GE022_RS00370 WP_003046007.1 56888..57799(+) (comR) [Streptococcus canis strain HL_77_2]
MLEHFGEKVKGLRQEKKISREDLCGDESELSVRQLARIELSQSIPSLAKVIFIAKALDVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDQLPEEEQVAIDIIQAKFEVYQTGNINFGSSILKEFLPQLKRKVIYNLNE
LLLIDLYLVTLVVSHFADDLFDRELYNKITERILKQNHHLMLEDLFLLNNILLSCADTSIRLEMFGRLKETLQLSHFIMS
TIQDFQRMPIYCMYEWKLSIFYLKDVERARNYYEQSILFTQMTSDYYLVERLHKEWHKDIQHI

Nucleotide


Download         Length: 912 bp        

>NTDB_id=447190 GE022_RS00370 WP_003046007.1 56888..57799(+) (comR) [Streptococcus canis strain HL_77_2]
ATGTTAGAGCATTTTGGTGAAAAAGTGAAAGGGCTAAGACAAGAGAAAAAGATTAGCAGAGAAGACTTATGTGGGGATGA
GTCTGAATTATCTGTTCGTCAACTAGCAAGGATTGAGTTGAGCCAGTCTATACCAAGTTTAGCCAAGGTTATTTTTATTG
CAAAAGCCTTAGATGTTAGCGTAGGTTATTTGACTGATGGGGCCAACCTTGAGTTACCCAAACGTTACAAAGAGTTAAAA
TATTTAATTCTGCGGACGCCAACTTATATGGATGATGGCAAATTACAAGTTCGAGAAGAACAGTTTGATGAGATATTTGA
GGATTACTATGACCAGCTGCCTGAGGAGGAGCAGGTGGCTATTGATATTATTCAAGCAAAATTTGAAGTTTACCAAACTG
GGAATATTAATTTTGGATCTAGTATTTTAAAAGAATTTTTACCACAACTTAAAAGGAAAGTTATTTATAATTTAAATGAG
TTGCTTTTGATAGATTTGTATTTAGTTACTTTGGTGGTTTCCCATTTTGCAGATGATTTATTTGACAGAGAGCTTTATAA
TAAGATTACAGAAAGAATTTTAAAACAAAACCATCATTTAATGTTGGAAGATTTATTTCTGCTGAATAATATTTTATTGT
CTTGTGCAGATACCTCTATTCGTTTAGAAATGTTTGGGAGGCTAAAAGAGACGTTACAACTCAGTCATTTCATTATGTCA
ACTATTCAAGATTTTCAAAGAATGCCAATTTATTGTATGTATGAGTGGAAGTTATCTATCTTTTATTTAAAAGATGTTGA
ACGTGCTCGAAATTATTATGAACAATCTATTTTATTTACTCAAATGACTAGTGATTATTACCTGGTTGAGAGACTTCACA
AAGAATGGCATAAAGATATTCAACATATATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

84.818

100

0.848
  comR Streptococcus pyogenes MGAS8232

55.629

99.67

0.554
  comR Streptococcus mutans UA159

48.344

99.67

0.482
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

44.746

97.36

0.436