Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GE023_RS01860 Genome accession   NZ_CP053789
Coordinates   345642..346403 (+) Length   253 a.a.
NCBI ID   WP_003046641.1    Uniprot ID   A0AAE4TTC6
Organism   Streptococcus canis strain HL_98_2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 340642..351403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS01835 (GE023_001835) - 340694..341584 (+) 891 WP_003046627.1 SPFH domain-containing protein -
  GE023_RS01840 (GE023_001840) - 341723..341839 (-) 117 WP_003046630.1 putative metal homeostasis protein -
  GE023_RS01845 (GE023_001845) - 341981..342721 (-) 741 WP_003046632.1 amino acid ABC transporter ATP-binding protein -
  GE023_RS01850 (GE023_001850) - 342714..344282 (-) 1569 WP_159305809.1 ABC transporter substrate-binding protein/permease -
  GE023_RS01855 (GE023_001855) - 344660..345499 (+) 840 WP_003046638.1 undecaprenyl-diphosphate phosphatase -
  GE023_RS01860 (GE023_001860) mecA 345642..346403 (+) 762 WP_003046641.1 adaptor protein MecA Regulator
  GE023_RS01865 (GE023_001865) - 346410..347579 (+) 1170 WP_164401804.1 glycosyltransferase family 4 protein -
  GE023_RS01870 (GE023_001870) sufC 347703..348473 (+) 771 WP_003046647.1 Fe-S cluster assembly ATPase SufC -
  GE023_RS01875 (GE023_001875) sufD 348572..349834 (+) 1263 WP_159305245.1 Fe-S cluster assembly protein SufD -
  GE023_RS01880 (GE023_001880) - 349865..351091 (+) 1227 WP_159305246.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29216.90 Da        Isoelectric Point: 4.0845

>NTDB_id=447146 GE023_RS01860 WP_003046641.1 345642..346403(+) (mecA) [Streptococcus canis strain HL_98_2]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKELNFEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEIMEDVVEATLTGQAEATDETHEVDPEPLDYVH
YVLDFDTLPEAITFAKTIDFPIEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEYATPGSKTRAYLQEHGLQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=447146 GE023_RS01860 WP_003046641.1 345642..346403(+) (mecA) [Streptococcus canis strain HL_98_2]
ATGGAAATGAAACAAATTAGCGAGACAACGCTGAAAATAACAATTAGTATGGATGATTTGGAAGAAAGAGGAATGGAGTT
AAAAGATTTTCTCATTCCCCAAGAAAAAACGGAAGAGTTCTTTTATTCTGTTATGGATGAACTAGATCTTCCAGATAATT
TTAAAGATAGTGGCATGCTTAGTTTTCGAGTAACACCAAGAAAAGACCGGCTAGATGTTTTTGTAACCAAATCTGAGCTT
AATAAGGAGCTTAACTTTGAAGATTTGGCAGATTTGGGTGATATTTCTCAAATGACACCTGAAGATTTTTTCAAAAGTTT
GGAGCAATCCATGCGTGAAAAAGGGGATGTCAATGCGCATGAGAAATTGGAAAAAATTGAAGAAATCATGGAAGATGTGG
TCGAAGCAACCTTAACTGGTCAGGCTGAGGCAACAGATGAAACGCATGAGGTCGATCCAGAACCATTGGATTATGTGCAC
TATGTTTTGGACTTTGATACCCTTCCAGAGGCGATAACCTTCGCCAAAACCATTGATTTCCCTATTGAAGCTTCAGAATT
ATACAAGGGTGACAGCCGTTACCACATGACCATTTTATTGGACGTTCAACAGCAGCCGTCATATTTTGCGAATGTTATGT
ATGCAAGGTTAATTGAGTATGCAACCCCTGGGTCAAAAACAAGAGCCTACTTGCAAGAGCATGGCTTACAATTGATTCTA
GATGGCGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

62.8

98.814

0.621
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.823

98.419

0.549
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.482
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.478
  mecA Streptococcus pneumoniae D39

47.826

100

0.478
  mecA Streptococcus pneumoniae R6

47.826

100

0.478