Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GE023_RS00340 Genome accession   NZ_CP053789
Coordinates   55288..56199 (+) Length   303 a.a.
NCBI ID   WP_003046007.1    Uniprot ID   A0AAE4Q9F2
Organism   Streptococcus canis strain HL_98_2     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 50288..61199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS00325 (GE023_000325) purE 51793..52284 (+) 492 WP_159305220.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  GE023_RS00330 (GE023_000330) purK 52271..53341 (+) 1071 WP_159305219.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  GE023_RS00335 (GE023_000335) purB 53859..55151 (+) 1293 WP_003046005.1 adenylosuccinate lyase -
  GE023_RS00340 (GE023_000340) comR 55288..56199 (+) 912 WP_003046007.1 helix-turn-helix domain-containing protein Regulator
  GE023_RS10745 comS 56286..56387 (+) 102 WP_201281440.1 quorum-sensing system DWW-type pheromone Regulator
  GE023_RS00345 (GE023_000345) ruvB 56420..57418 (+) 999 WP_003046011.1 Holliday junction branch migration DNA helicase RuvB -
  GE023_RS00350 (GE023_000350) - 57559..58002 (+) 444 WP_159305976.1 low molecular weight protein-tyrosine-phosphatase -
  GE023_RS00355 (GE023_000355) - 58019..58420 (+) 402 WP_003046016.1 MORN repeat-containing protein -
  GE023_RS00360 (GE023_000360) - 58417..60192 (+) 1776 WP_159305977.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 36092.66 Da        Isoelectric Point: 5.0503

>NTDB_id=447135 GE023_RS00340 WP_003046007.1 55288..56199(+) (comR) [Streptococcus canis strain HL_98_2]
MLEHFGEKVKGLRQEKKISREDLCGDESELSVRQLARIELSQSIPSLAKVIFIAKALDVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDQLPEEEQVAIDIIQAKFEVYQTGNINFGSSILKEFLPQLKRKVIYNLNE
LLLIDLYLVTLVVSHFADDLFDRELYNKITERILKQNHHLMLEDLFLLNNILLSCADTSIRLEMFGRLKETLQLSHFIMS
TIQDFQRMPIYCMYEWKLSIFYLKDVERARNYYEQSILFTQMTSDYYLVERLHKEWHKDIQHI

Nucleotide


Download         Length: 912 bp        

>NTDB_id=447135 GE023_RS00340 WP_003046007.1 55288..56199(+) (comR) [Streptococcus canis strain HL_98_2]
ATGTTAGAGCATTTTGGTGAAAAAGTGAAAGGGCTAAGACAAGAGAAAAAGATTAGCAGAGAAGACTTATGTGGGGATGA
GTCTGAATTATCTGTTCGTCAACTAGCGAGGATTGAGTTGAGCCAGTCTATACCAAGTTTAGCCAAGGTTATTTTTATTG
CAAAAGCCTTAGATGTTAGCGTAGGTTATTTGACTGATGGGGCCAACCTTGAGTTACCCAAACGTTACAAAGAGTTAAAA
TATTTAATTCTGCGGACGCCAACTTATATGGATGATGGCAAATTACAAGTTCGAGAAGAACAGTTTGATGAGATATTTGA
GGATTACTATGACCAGCTGCCTGAGGAGGAGCAGGTGGCTATTGATATTATTCAAGCAAAATTTGAAGTTTACCAAACTG
GGAATATTAATTTTGGATCTAGTATTTTAAAAGAATTTTTACCACAACTTAAAAGGAAAGTTATTTATAATTTAAATGAG
TTGCTTTTGATAGATTTGTATTTAGTTACTTTGGTGGTTTCCCATTTTGCAGATGATTTATTTGACAGAGAGCTTTATAA
TAAGATTACAGAAAGAATTTTAAAACAAAACCATCATTTAATGTTGGAAGATTTATTTCTGCTGAATAATATTTTATTGT
CTTGTGCAGATACCTCTATTCGTTTAGAAATGTTTGGGAGGCTAAAAGAGACGTTACAACTCAGTCATTTCATTATGTCA
ACTATTCAAGATTTTCAAAGAATGCCAATTTATTGTATGTATGAGTGGAAGTTATCTATCTTTTATTTAAAAGATGTTGA
ACGTGCTCGAAATTATTATGAACAATCTATTTTATTTACTCAAATGACTAGTGATTATTACCTGGTTGAGAGACTTCACA
AAGAATGGCATAAAGATATTCAACATATATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS315

84.818

100

0.848
  comR Streptococcus pyogenes MGAS8232

55.629

99.67

0.554
  comR Streptococcus mutans UA159

48.344

99.67

0.482
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

44.746

97.36

0.436