Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C270_RS01545 Genome accession   NC_018673
Coordinates   283810..284676 (+) Length   288 a.a.
NCBI ID   WP_014973798.1    Uniprot ID   K0D5Q6
Organism   Leuconostoc carnosum JB16     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 278810..289676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C270_RS01525 - 279439..280227 (+) 789 WP_041773140.1 Sua5/YciO/YrdC/YwlC family protein -
  C270_RS01530 (C270_01310) - 280519..281544 (+) 1026 WP_014973795.1 nickel permease -
  C270_RS01535 (C270_01315) ciaR 281789..282478 (+) 690 WP_014973796.1 response regulator transcription factor Regulator
  C270_RS01540 (C270_01320) - 282471..283754 (+) 1284 WP_014973797.1 HAMP domain-containing sensor histidine kinase -
  C270_RS01545 (C270_01325) htrA 283810..284676 (+) 867 WP_014973798.1 trypsin-like peptidase domain-containing protein Regulator
  C270_RS01550 (C270_01330) - 284758..285756 (-) 999 WP_014973799.1 AI-2E family transporter -
  C270_RS01555 (C270_01335) - 285926..286252 (-) 327 WP_014973800.1 thioredoxin family protein -
  C270_RS01560 (C270_01340) - 286817..287695 (+) 879 WP_014973801.1 homoserine O-succinyltransferase -
  C270_RS01565 (C270_01345) - 287720..288829 (+) 1110 WP_014973802.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 29635.08 Da        Isoelectric Point: 8.2995

>NTDB_id=44645 C270_RS01545 WP_014973798.1 283810..284676(+) (htrA) [Leuconostoc carnosum JB16]
MKHSLITVAVISALVGGGVVYSGTQDNSWFQKPTAITKTSNLSGQATIAKTAYTSNDTSTTAYNKVKNAVLTVQNLQKSS
GQQRDAWSTMFGSDSQNNSNSSELQTASEGSGVVYKIKDGYAYIITNNHVVADSDALQLITASGKKVKATIVGTDPQKDL
ALIKAQTDVIKTAATFGSVKQLQSGQQVLAIGSPLGSDYATSMTSGIVSAARRTLTAEETGAATATAIQTDAAINPGNSG
GPLVNLSGQVVGINSSKIAASTDGTSVEGMGFAIPADIVQAFIDKTEK

Nucleotide


Download         Length: 867 bp        

>NTDB_id=44645 C270_RS01545 WP_014973798.1 283810..284676(+) (htrA) [Leuconostoc carnosum JB16]
ATGAAACACTCTCTTATAACAGTAGCTGTTATTTCAGCACTGGTTGGTGGTGGCGTGGTTTATTCCGGAACGCAAGACAA
TTCGTGGTTTCAAAAACCAACTGCTATTACAAAAACATCGAATTTATCTGGTCAAGCTACAATTGCAAAAACGGCTTATA
CGAGTAATGACACGTCTACAACAGCGTATAATAAAGTTAAAAATGCTGTGCTGACTGTACAAAACTTACAAAAATCATCC
GGCCAACAAAGAGATGCATGGTCAACTATGTTCGGTTCAGATTCTCAAAATAATAGTAACTCCTCGGAATTACAAACCGC
ATCTGAGGGTTCTGGTGTTGTTTATAAAATAAAAGATGGCTATGCTTACATTATTACAAACAATCACGTTGTTGCCGATT
CTGACGCTTTGCAATTAATTACGGCGAGTGGCAAAAAGGTGAAAGCGACGATTGTGGGGACAGATCCGCAAAAAGATCTG
GCTTTAATCAAAGCGCAAACAGATGTGATTAAGACGGCAGCGACATTTGGTTCAGTGAAACAGTTACAATCTGGGCAACA
GGTTTTGGCTATCGGGTCACCTTTAGGCTCTGATTATGCGACATCGATGACAAGCGGCATCGTTTCAGCTGCACGCCGGA
CACTAACCGCTGAAGAGACAGGGGCAGCCACTGCAACCGCAATTCAGACTGATGCTGCCATTAATCCTGGTAACTCTGGT
GGTCCGTTAGTTAATCTATCTGGTCAAGTAGTGGGAATCAATTCATCAAAAATAGCTGCATCAACGGATGGTACAAGCGT
GGAAGGCATGGGATTTGCTATTCCAGCAGATATTGTTCAAGCATTTATTGATAAAACTGAAAAGTAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(110-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0D5Q6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

46.643

98.264

0.458
  htrA Streptococcus mitis NCTC 12261

43.478

100

0.451
  htrA Streptococcus mutans UA159

47.431

87.847

0.417
  htrA Streptococcus pneumoniae TIGR4

46.311

84.722

0.392
  htrA Streptococcus pneumoniae Rx1

46.311

84.722

0.392
  htrA Streptococcus pneumoniae D39

46.311

84.722

0.392
  htrA Streptococcus pneumoniae R6

46.311

84.722

0.392

Multiple sequence alignment