Detailed information NTG0446203

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: HPC60_RS09800
• Genome accession: NZ_CP053671
• Coordinates: 1964946..1967156 (-)
• Length: 736 a.a.
• NCBI ID: WP_179107682.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain G121
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1959946..1972156

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPC60_RS09770 (HPC60_04515)	atpA	1959988..1961490 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
HPC60_RS09775 (HPC60_04520)	-	1961677..1962204 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
HPC60_RS09780 (HPC60_04525)	atpF	1962206..1962712 (-)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-
HPC60_RS09785 (HPC60_04530)	atpB	1962727..1963440 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
HPC60_RS09790 (HPC60_04535)	-	1963485..1963700 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
HPC60_RS09795 (HPC60_04540)	-	1963885..1964661 (-)	777	WP_023188533.1	alpha/beta hydrolase family protein	-
HPC60_RS09800 (HPC60_04545)	comEC	1964946..1967156 (-)	2211	WP_179107682.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
HPC60_RS09805 (HPC60_04550)	comEA	1967137..1967784 (-)	648	WP_179107683.1	ComEA family DNA-binding protein	Machinery gene
HPC60_RS09810 (HPC60_04555)	-	1967844..1969205 (-)	1362	WP_025016984.1	ABC transporter permease	-
HPC60_RS09815 (HPC60_04560)	-	1969202..1970134 (-)	933	WP_025016985.1	ABC transporter ATP-binding protein	-
HPC60_RS09820 (HPC60_04565)	-	1970239..1970637 (-)	399	WP_023188528.1	hypothetical protein	-
HPC60_RS09825 (HPC60_04570)	-	1970741..1971304 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84570.20 Da
• Isoelectric Point: 9.6385

>NTDB_id=446203 HPC60_RS09800 WP_179107682.1 1964946..1967156(-) (comEC) [Lactococcus lactis subsp. lactis strain G121]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLLCLILFIFSSLLASYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERDQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQDI
YRQITIDKINKIVLNDTFDLRVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALLGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=446203 HPC60_RS09800 WP_179107682.1 1964946..1967156(-) (comEC) [Lactococcus lactis subsp. lactis strain G121]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTACTTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTCATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGACCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGGATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCGTGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATTGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.359	100	0.764
comEC/celB	Streptococcus mitis SK321	44.489	100	0.45
comEC/celB	Streptococcus mitis NCTC 12261	44.28	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.28	100	0.438
comEC/celB	Streptococcus pneumoniae Rx1	42.876	100	0.433
comEC/celB	Streptococcus pneumoniae D39	42.876	100	0.433
comEC/celB	Streptococcus pneumoniae R6	42.876	100	0.433