NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	H7994_RS04240	Genome accession	NZ_CP065152
Coordinates	864358..865482 (-)	Length	374 a.a.
NCBI ID	WP_097521004.1	Uniprot ID	-
Organism	Escherichia coli O150:H6 strain FEX669
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 859358..870482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7994_RS04210 (H7994_04210)	yrdA	861158..861712 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
H7994_RS04215 (H7994_04215)	yrdB	861688..861945 (-)	258	WP_001070567.1	DUF1488 domain-containing protein	-
H7994_RS04220 (H7994_04220)	aroE	861942..862760 (-)	819	WP_000451230.1	shikimate dehydrogenase	-
H7994_RS04225 (H7994_04225)	tsaC	862765..863337 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
H7994_RS04230 (H7994_04230)	yrdD	863342..863884 (-)	543	WP_001312137.1	type I DNA topoisomerase	-
H7994_RS04235 (H7994_04235)	smg	863913..864386 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
H7994_RS04240 (H7994_04240)	dprA	864358..865482 (-)	1125	WP_097521004.1	DNA-protecting protein DprA	Machinery gene
H7994_RS04245 (H7994_04245)	def	865612..866121 (+)	510	WP_000114984.1	peptide deformylase	-
H7994_RS04250 (H7994_04250)	fmt	866136..867083 (+)	948	WP_097317179.1	methionyl-tRNA formyltransferase	-
H7994_RS04255 (H7994_04255)	rsmB	867135..868424 (+)	1290	WP_097317178.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
H7994_RS04260 (H7994_04260)	trkA	868446..869822 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
H7994_RS04265 (H7994_04265)	mscL	869952..870365 (+)	414	WP_000022450.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40940.88 Da Isoelectric Point: 6.0395

                                >NTDB_id=445657 H7994_RS04240 WP_097521004.1 864358..865482(-) (dprA) [Escherichia coli O150:H6 strain FEX669]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKATLQVN

GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=445657 H7994_RS04240 WP_097521004.1 864358..865482(-) (dprA) [Escherichia coli O150:H6 strain FEX669]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTTG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGACCTTACAGGTAAAT

GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT

TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAGGGGGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.032	82.888	0.406
dprA	Vibrio cholerae strain A1552	49.032	82.888	0.406
dprA	Glaesserella parasuis strain SC1401	44.51	90.107	0.401
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.242	88.235	0.39

Detailed information NTG0445657