Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IPT86_RS21295 Genome accession   NZ_CP064847
Coordinates   4416139..4417263 (-) Length   374 a.a.
NCBI ID   WP_000228525.1    Uniprot ID   -
Organism   Escherichia coli strain 20     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4411139..4422263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IPT86_RS21265 (IPT86_21265) yrdA 4412939..4413493 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  IPT86_RS21270 (IPT86_21270) yrdB 4413469..4413726 (-) 258 WP_001070584.1 DUF1488 domain-containing protein -
  IPT86_RS21275 (IPT86_21275) aroE 4413723..4414541 (-) 819 WP_000451226.1 shikimate dehydrogenase -
  IPT86_RS21280 (IPT86_21280) tsaC 4414546..4415118 (-) 573 WP_001361937.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  IPT86_RS21285 (IPT86_21285) yrdD 4415123..4415665 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  IPT86_RS21290 (IPT86_21290) smg 4415694..4416167 (-) 474 WP_000460682.1 DUF494 family protein Smg -
  IPT86_RS21295 (IPT86_21295) dprA 4416139..4417263 (-) 1125 WP_000228525.1 DNA-protecting protein DprA Machinery gene
  IPT86_RS21300 (IPT86_21300) def 4417393..4417902 (+) 510 WP_000114986.1 peptide deformylase -
  IPT86_RS21305 (IPT86_21305) fmt 4417917..4418864 (+) 948 WP_000004466.1 methionyl-tRNA formyltransferase -
  IPT86_RS21310 (IPT86_21310) rsmB 4418910..4420199 (+) 1290 WP_001361938.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IPT86_RS21315 (IPT86_21315) trkA 4420221..4421597 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  IPT86_RS21320 (IPT86_21320) mscL 4421727..4422137 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40933.83 Da        Isoelectric Point: 6.1402

>NTDB_id=445317 IPT86_RS21295 WP_000228525.1 4416139..4417263(-) (dprA) [Escherichia coli strain 20]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=445317 IPT86_RS21295 WP_000228525.1 4416139..4417263(-) (dprA) [Escherichia coli strain 20]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCTCCACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Legionella pneumophila strain ERS1305867

43.363

90.642

0.393
  dprA Haemophilus influenzae Rd KW20

43.62

90.107

0.393