Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   HKM25_RS11210 Genome accession   NZ_CP053210
Coordinates   2188136..2188798 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain 6A-10     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2183136..2193798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS11185 (HKM25_2300) - 2183286..2183552 (-) 267 WP_001278167.1 Veg family protein -
  HKM25_RS11190 (HKM25_2301) dnaB 2183554..2184906 (-) 1353 WP_000852486.1 replicative DNA helicase -
  HKM25_RS11195 (HKM25_2302) rplI 2184950..2185402 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  HKM25_RS11200 (HKM25_2303) - 2185399..2187372 (-) 1974 WP_170835816.1 DHH family phosphoesterase -
  HKM25_RS11205 (HKM25_2304) raiA 2187508..2188056 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  HKM25_RS11210 (HKM25_2305) comFC/cflB 2188136..2188798 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  HKM25_RS11215 (HKM25_2306) comFA/cflA 2188795..2190093 (-) 1299 WP_000867613.1 DEAD/DEAH box helicase Machinery gene
  HKM25_RS11220 (HKM25_2307) - 2190149..2190784 (+) 636 WP_000395747.1 YigZ family protein -
  HKM25_RS11225 (HKM25_2308) cysK 2191033..2191959 (+) 927 WP_000029870.1 cysteine synthase A -
  HKM25_RS11230 (HKM25_2309) tsf 2192080..2193120 (-) 1041 WP_000808062.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=443486 HKM25_RS11210 WP_000649971.1 2188136..2188798(-) (comFC/cflB) [Streptococcus pneumoniae strain 6A-10]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=443486 HKM25_RS11210 WP_000649971.1 2188136..2188798(-) (comFC/cflB) [Streptococcus pneumoniae strain 6A-10]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914