Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HLB22_RS13670 Genome accession   NZ_CP053101
Coordinates   2743544..2744209 (-) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain EDCC5398     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2738544..2749209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLB22_RS13650 (HLB22_13660) - 2739009..2739122 (-) 114 WP_072384844.1 hypothetical protein -
  HLB22_RS13655 (HLB22_13665) - 2739786..2741786 (-) 2001 WP_000776746.1 ABC transporter permease -
  HLB22_RS13660 (HLB22_13670) - 2741783..2742538 (-) 756 WP_001670202.1 ABC transporter ATP-binding protein -
  HLB22_RS13665 (HLB22_13675) braS 2742646..2743533 (-) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  HLB22_RS13670 (HLB22_13680) braR 2743544..2744209 (-) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  HLB22_RS13675 (HLB22_13685) - 2744235..2744435 (-) 201 WP_000604723.1 hypothetical protein -
  HLB22_RS13680 (HLB22_13690) - 2744633..2746057 (+) 1425 WP_000953731.1 alkaline phosphatase -
  HLB22_RS13685 (HLB22_13695) - 2746127..2746237 (+) 111 WP_001791296.1 hypothetical protein -
  HLB22_RS13690 (HLB22_13700) - 2746340..2746795 (-) 456 WP_000106184.1 MarR family transcriptional regulator -
  HLB22_RS13695 (HLB22_13705) - 2747041..2747802 (-) 762 WP_170267450.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=443056 HLB22_RS13670 WP_000697883.1 2743544..2744209(-) (braR) [Staphylococcus aureus strain EDCC5398]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=443056 HLB22_RS13670 WP_000697883.1 2743544..2744209(-) (braR) [Staphylococcus aureus strain EDCC5398]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACGGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGACAATACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATTATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995