Detailed information NTG0044215

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: HMPREF1038_RS06425
• Genome accession: NC_018630
• Coordinates: 1214328..1214969 (-)
• Length: 213 a.a.
• NCBI ID: WP_000151483.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae gamPNI0373
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1209328..1219969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF1038_RS06395 (HMPREF1038_01305)	-	1209448..1209690 (+)	243	WP_000710764.1	type B 50S ribosomal protein L31	-
HMPREF1038_RS06400 (HMPREF1038_01306)	-	1209747..1210292 (-)	546	WP_001844616.1	hypothetical protein	-
HMPREF1038_RS06405 (HMPREF1038_01307)	-	1210300..1211312 (-)	1013	Protein_1224	Dyp-type peroxidase	-
HMPREF1038_RS11785 (HMPREF1038_01309)	-	1211282..1211773 (-)	492	Protein_1225	winged helix-turn-helix domain-containing protein	-
HMPREF1038_RS06415 (HMPREF1038_01310)	gdhA	1212303..1213649 (+)	1347	WP_000199558.1	NADP-specific glutamate dehydrogenase	-
HMPREF1038_RS06420 (HMPREF1038_01311)	-	1214145..1214315 (-)	171	WP_000711943.1	hypothetical protein	-
HMPREF1038_RS06425 (HMPREF1038_01312)	comA	1214328..1214969 (-)	642	WP_000151483.1	ATP-binding cassette domain-containing protein	Regulator
HMPREF1038_RS13550	-	1215094..1215281 (-)	188	Protein_1229	hypothetical protein	-
HMPREF1038_RS11795	-	1215568..1216913 (-)	1346	Protein_1230	IS1380-like element ISSpn5 family transposase	-
HMPREF1038_RS06440 (HMPREF1038_01315)	-	1217090..1217545 (+)	456	WP_000459732.1	transposase	-
HMPREF1038_RS06445 (HMPREF1038_01316)	-	1217695..1217889 (-)	195	Protein_1232	ROK family protein	-
HMPREF1038_RS06450 (HMPREF1038_01317)	-	1217916..1218833 (-)	918	WP_001281505.1	dihydrodipicolinate synthase family protein	-
HMPREF1038_RS06455 (HMPREF1038_01318)	-	1218865..1219272 (-)	408	WP_000216069.1	cytidine deaminase	-

Sequence

Protein

• Length: 213 a.a.
• Molecular weight: 23486.26 Da
• Isoelectric Point: 9.2387

>NTDB_id=44215 HMPREF1038_RS06425 WP_000151483.1 1214328..1214969(-) (comA) [Streptococcus pneumoniae gamPNI0373]
MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEV
TSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK

Nucleotide

• Length: 642 bp

>NTDB_id=44215 HMPREF1038_RS06425 WP_000151483.1 1214328..1214969(-) (comA) [Streptococcus pneumoniae gamPNI0373]
TTGACTATTGAGTCAGGACAGAGAATTGCACTAGTCGGTCAACCGGGGTCAGGAAAAAGTACATTATCAAAAATACCATC
AGGATTATATAAGATTGATACAGGAAAAGTTTTATTTGATGGTGTAAATATTAATCAAATAGATAAAAAAATATTAAGTC
AAAATTTAGGAGTAGTTCCACAGGATTCGTTTTTATTGAACAGAAGTATTCTTGATAACATAACTTTAAAGCACGAAGTT
ACTTCACAAAAGATAGAGGAAGTTTGTAAAGCAGTTCAAATCTATGATGAAATCATGGCTATGCCGATGAAATTTAATAC
TATCATCTCAGAGATGGGTTCAAATATTTCAGGTGGTCAAAGACAACGGATAGCACTGGCACGTGCATTAATAAATAATC
CTAGTATTGTAATTTTAGATGAAGCAACTAGTGCTTTAGACACTATTAATGAGGAAAGAATAACAAAGTATATAAAAAGT
CAGGGCTGTACTCAAATAATTGTAGCTCATAGATTGTCAACGATTAAGGATGCGGATATTATTGTTGTAATGAAAGGTGG
TAAGATTGTTGAGTCAGGAAATCATAAGTACTTAATGGATCTTGGTGGAGAGTACTACAGCTTATATACAAAAAGGAAAT
GA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (1-144)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	43.333	98.592	0.427
comA	Streptococcus mitis SK321	42.857	98.592	0.423
comA	Streptococcus gordonii str. Challis substr. CH1	41.981	99.531	0.418
comA/nlmT	Streptococcus mutans UA159	41.981	99.531	0.418
comA	Streptococcus pneumoniae R6	41.905	98.592	0.413
comA	Streptococcus pneumoniae Rx1	41.905	98.592	0.413
comA	Streptococcus pneumoniae D39	41.905	98.592	0.413
comA	Streptococcus pneumoniae TIGR4	40.952	98.592	0.404
rcrQ	Streptococcus mutans UA159	36.62	100	0.366