Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   IRJ24_RS05875 Genome accession   NZ_CP064093
Coordinates   1121050..1122252 (+) Length   400 a.a.
NCBI ID   WP_009969578.1    Uniprot ID   P39668
Organism   Bacillus subtilis strain N1282-4at     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1116050..1127252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IRJ24_RS05855 walK 1116131..1117966 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  IRJ24_RS05860 walH 1117956..1119323 (+) 1368 WP_003242498.1 WalRK two-component regulatory system regulator WalH -
  IRJ24_RS05865 walI 1119310..1120152 (+) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  IRJ24_RS05870 vicX 1120174..1120968 (+) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  IRJ24_RS05875 htrA 1121050..1122252 (+) 1203 WP_009969578.1 serine protease HtrC Regulator
  IRJ24_RS05880 - 1122272..1122400 (+) 129 WP_003242634.1 hypothetical protein -
  IRJ24_RS05885 - 1122517..1122705 (+) 189 Protein_1089 ATP-binding protein -
  IRJ24_RS05890 rocR 1122687..1124072 (-) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  IRJ24_RS05895 rocD 1124313..1125518 (+) 1206 WP_003242970.1 ornithine aminotransferase -
  IRJ24_RS05900 rocE 1125741..1127144 (+) 1404 WP_003242721.1 amino acid permease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42788.56 Da        Isoelectric Point: 5.3354

>NTDB_id=441705 IRJ24_RS05875 WP_009969578.1 1121050..1122252(+) (htrA) [Bacillus subtilis strain N1282-4at]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNMSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=441705 IRJ24_RS05875 WP_009969578.1 1121050..1122252(+) (htrA) [Bacillus subtilis strain N1282-4at]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATATGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCTGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCTGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(203-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P39668

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

42.746

96.5

0.412
  htrA Streptococcus pneumoniae TIGR4

44.848

82.5

0.37
  htrA Streptococcus pneumoniae D39

44.848

82.5

0.37
  htrA Streptococcus pneumoniae Rx1

44.848

82.5

0.37
  htrA Streptococcus pneumoniae R6

44.848

82.5

0.37