Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IQS16_RS20185 Genome accession   NZ_CP063518
Coordinates   4213428..4214552 (-) Length   374 a.a.
NCBI ID   WP_000228538.1    Uniprot ID   -
Organism   Escherichia coli strain EH01-18-02     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 4208428..4219552
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQS16_RS20155 (IQS16_20150) yrdA 4210228..4210761 (+) 534 WP_203158281.1 gamma carbonic anhydrase family protein -
  IQS16_RS20160 (IQS16_20155) yrdB 4210758..4211015 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  IQS16_RS20165 (IQS16_20160) aroE 4211012..4211830 (-) 819 WP_000451211.1 shikimate dehydrogenase -
  IQS16_RS20170 (IQS16_20165) tsaC 4211835..4212407 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  IQS16_RS20175 (IQS16_20170) yrdD 4212412..4212954 (-) 543 WP_001129724.1 type I DNA topoisomerase -
  IQS16_RS20180 (IQS16_20175) smg 4212983..4213456 (-) 474 WP_000460670.1 DUF494 family protein Smg -
  IQS16_RS20185 (IQS16_20180) dprA 4213428..4214552 (-) 1125 WP_000228538.1 DNA-protecting protein DprA Machinery gene
  IQS16_RS20190 (IQS16_20185) def 4214682..4215191 (+) 510 WP_000114984.1 peptide deformylase -
  IQS16_RS20195 (IQS16_20190) fmt 4215206..4216153 (+) 948 WP_000004454.1 methionyl-tRNA formyltransferase -
  IQS16_RS20200 (IQS16_20195) rsmB 4216199..4217488 (+) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IQS16_RS20205 (IQS16_20200) trkA 4217510..4218886 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  IQS16_RS20210 (IQS16_20205) mscL 4219016..4219426 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40955.86 Da        Isoelectric Point: 6.3122

>NTDB_id=440587 IQS16_RS20185 WP_000228538.1 4213428..4214552(-) (dprA) [Escherichia coli strain EH01-18-02]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=440587 IQS16_RS20185 WP_000228538.1 4213428..4214552(-) (dprA) [Escherichia coli strain EH01-18-02]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

45.135

98.93

0.447
  dprA Vibrio cholerae strain A1552

45.135

98.93

0.447
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Glaesserella parasuis strain SC1401

45.133

90.642

0.409
  dprA Legionella pneumophila strain ERS1305867

44.848

88.235

0.396