NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	IQS19_RS21505	Genome accession	NZ_CP063503
Coordinates	4465931..4467055 (-)	Length	374 a.a.
NCBI ID	WP_000228555.1	Uniprot ID	-
Organism	Escherichia coli strain EH09-18-41
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4460931..4472055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IQS19_RS21475 (IQS19_21480)	yrdA	4462731..4463285 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
IQS19_RS21480 (IQS19_21485)	yrdB	4463261..4463518 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
IQS19_RS21485 (IQS19_21490)	aroE	4463515..4464333 (-)	819	WP_000451218.1	shikimate dehydrogenase	-
IQS19_RS21490 (IQS19_21495)	tsaC	4464338..4464910 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
IQS19_RS21495 (IQS19_21500)	yrdD	4464915..4465457 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
IQS19_RS21500 (IQS19_21505)	smg	4465486..4465959 (-)	474	WP_000460670.1	DUF494 family protein Smg	-
IQS19_RS21505 (IQS19_21510)	dprA	4465931..4467055 (-)	1125	WP_000228555.1	DNA-protecting protein DprA	Machinery gene
IQS19_RS21510 (IQS19_21515)	def	4467185..4467694 (+)	510	WP_000114985.1	peptide deformylase	-
IQS19_RS21515 (IQS19_21520)	fmt	4467709..4468656 (+)	948	WP_000004438.1	methionyl-tRNA formyltransferase	-
IQS19_RS21520 (IQS19_21525)	rsmB	4468702..4469991 (+)	1290	WP_000744778.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
IQS19_RS21525 (IQS19_21530)	trkA	4470013..4471389 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
IQS19_RS21530 (IQS19_21535)	mscL	4471519..4471929 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40994.94 Da Isoelectric Point: 6.2655

                                >NTDB_id=440346 IQS19_RS21505 WP_000228555.1 4465931..4467055(-) (dprA) [Escherichia coli strain EH09-18-41]

MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=440346 IQS19_RS21505 WP_000228555.1 4465931..4467055(-) (dprA) [Escherichia coli strain EH09-18-41]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG

GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGTATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTTTAAGTAAAGGCGTACTGGTGGTGGAAGCTGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCTGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAATTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.238	98.663	0.476
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0440346