Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   HHM65_RS03255 Genome accession   NZ_CP051624
Coordinates   592839..593549 (+) Length   236 a.a.
NCBI ID   WP_003057225.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 587839..598549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS03230 (HHM65_03235) - 588518..589513 (+) 996 WP_003057220.1 DUF3114 domain-containing protein -
  HHM65_RS03235 (HHM65_03240) - 589609..590256 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  HHM65_RS03240 (HHM65_03245) - 590271..590972 (-) 702 WP_015057398.1 amino acid ABC transporter permease -
  HHM65_RS03245 (HHM65_03250) - 590986..591786 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  HHM65_RS03250 (HHM65_03255) - 591786..592580 (-) 795 WP_015057400.1 amino acid ABC transporter ATP-binding protein -
  HHM65_RS03255 (HHM65_03260) vicR 592839..593549 (+) 711 WP_003057225.1 response regulator YycF Regulator
  HHM65_RS03260 (HHM65_03265) vicK 593542..594894 (+) 1353 WP_014612101.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HHM65_RS03265 (HHM65_03270) vicX 594898..595707 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  HHM65_RS03270 (HHM65_03275) rnc 596465..597157 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27071.98 Da        Isoelectric Point: 5.0023

>NTDB_id=439890 HHM65_RS03255 WP_003057225.1 592839..593549(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGIGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=439890 HHM65_RS03255 WP_003057225.1 592839..593549(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTATTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

37.712

100

0.377