Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IQS25_RS18275 Genome accession   NZ_CP063467
Coordinates   3809618..3810742 (+) Length   374 a.a.
NCBI ID   WP_203139826.1    Uniprot ID   -
Organism   Escherichia coli strain EM20-18-50     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3804618..3815742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQS25_RS18250 (IQS25_18260) mscL 3804744..3805154 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  IQS25_RS18255 (IQS25_18265) trkA 3805284..3806660 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  IQS25_RS18260 (IQS25_18270) rsmB 3806682..3807971 (-) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IQS25_RS18265 (IQS25_18275) fmt 3808017..3808964 (-) 948 WP_203139824.1 methionyl-tRNA formyltransferase -
  IQS25_RS18270 (IQS25_18280) def 3808979..3809488 (-) 510 WP_000114984.1 peptide deformylase -
  IQS25_RS18275 (IQS25_18285) dprA 3809618..3810742 (+) 1125 WP_203139826.1 DNA-protecting protein DprA Machinery gene
  IQS25_RS18280 (IQS25_18290) smg 3810714..3811187 (+) 474 WP_000460680.1 DUF494 family protein Smg -
  IQS25_RS18285 (IQS25_18295) yrdD 3811216..3811758 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  IQS25_RS18290 (IQS25_18300) tsaC 3811763..3812335 (+) 573 WP_089075108.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  IQS25_RS18295 (IQS25_18305) aroE 3812340..3813158 (+) 819 WP_000451243.1 shikimate dehydrogenase -
  IQS25_RS18300 (IQS25_18310) yrdB 3813155..3813412 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  IQS25_RS18305 (IQS25_18315) yrdA 3813388..3813942 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40944.88 Da        Isoelectric Point: 6.3122

>NTDB_id=439686 IQS25_RS18275 WP_203139826.1 3809618..3810742(+) (dprA) [Escherichia coli strain EM20-18-50]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPSLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=439686 IQS25_RS18275 WP_203139826.1 3809618..3810742(+) (dprA) [Escherichia coli strain EM20-18-50]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCATCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAGCGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388