Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IN878_RS11965 Genome accession   NZ_CP063332
Coordinates   2434119..2435243 (-) Length   374 a.a.
NCBI ID   WP_000228553.1    Uniprot ID   -
Organism   Escherichia coli strain BS74R-D     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2429119..2440243
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IN878_RS11935 (IN878_11945) yrdA 2430919..2431473 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  IN878_RS11940 (IN878_11950) yrdB 2431449..2431706 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  IN878_RS11945 (IN878_11955) aroE 2431703..2432521 (-) 819 WP_000451243.1 shikimate dehydrogenase -
  IN878_RS11950 (IN878_11960) tsaC 2432526..2433098 (-) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  IN878_RS11955 (IN878_11965) yrdD 2433103..2433645 (-) 543 WP_001129722.1 type I DNA topoisomerase -
  IN878_RS11960 (IN878_11970) smg 2433674..2434147 (-) 474 WP_000460680.1 DUF494 family protein Smg -
  IN878_RS11965 (IN878_11975) dprA 2434119..2435243 (-) 1125 WP_000228553.1 DNA-protecting protein DprA Machinery gene
  IN878_RS11970 (IN878_11980) def 2435373..2435882 (+) 510 WP_000114984.1 peptide deformylase -
  IN878_RS11975 (IN878_11985) fmt 2435897..2436844 (+) 948 WP_000004473.1 methionyl-tRNA formyltransferase -
  IN878_RS11980 (IN878_11990) rsmB 2436890..2438179 (+) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  IN878_RS11985 (IN878_11995) trkA 2438201..2439577 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  IN878_RS11990 (IN878_12000) mscL 2439707..2440117 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40944.88 Da        Isoelectric Point: 6.3122

>NTDB_id=437838 IN878_RS11965 WP_000228553.1 2434119..2435243(-) (dprA) [Escherichia coli strain BS74R-D]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFSRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=437838 IN878_RS11965 WP_000228553.1 2434119..2435243(-) (dprA) [Escherichia coli strain BS74R-D]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCTCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388