NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	INR48_RS19795	Genome accession	NZ_CP063153
Coordinates	4147333..4148457 (-)	Length	374 a.a.
NCBI ID	WP_000228541.1	Uniprot ID	-
Organism	Escherichia coli strain M7424
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4142333..4153457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INR48_RS19765 (INR48_19770)	yrdA	4144133..4144687 (+)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-
INR48_RS19770 (INR48_19775)	yrdB	4144663..4144920 (-)	258	WP_001070562.1	DUF1488 domain-containing protein	-
INR48_RS19775 (INR48_19780)	aroE	4144917..4145735 (-)	819	WP_000451230.1	shikimate dehydrogenase	-
INR48_RS19780 (INR48_19785)	tsaC	4145740..4146312 (-)	573	WP_001310090.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
INR48_RS19785 (INR48_19790)	yrdD	4146317..4146859 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
INR48_RS19790 (INR48_19795)	smg	4146888..4147361 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
INR48_RS19795 (INR48_19800)	dprA	4147333..4148457 (-)	1125	WP_000228541.1	DNA-protecting protein DprA	Machinery gene
INR48_RS19800 (INR48_19805)	def	4148587..4149096 (+)	510	WP_000114984.1	peptide deformylase	-
INR48_RS19805 (INR48_19810)	fmt	4149111..4150058 (+)	948	WP_000004443.1	methionyl-tRNA formyltransferase	-
INR48_RS19810 (INR48_19815)	rsmB	4150104..4151393 (+)	1290	WP_001309796.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
INR48_RS19815 (INR48_19820)	trkA	4151415..4152791 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
INR48_RS19820 (INR48_19825)	mscL	4152921..4153331 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41061.04 Da Isoelectric Point: 6.0799

                                >NTDB_id=437383 INR48_RS19795 WP_000228541.1 4147333..4148457(-) (dprA) [Escherichia coli strain M7424]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSYIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELYALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=437383 INR48_RS19795 WP_000228541.1 4147333..4148457(-) (dprA) [Escherichia coli strain M7424]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGTATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGTACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGACGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	43.62	90.107	0.393
dprA	Legionella pneumophila strain ERS1305867	44.073	87.968	0.388

Detailed information NTG0437383