Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HED61_RS14070 Genome accession   NZ_CP050816
Coordinates   2883070..2884377 (+) Length   435 a.a.
NCBI ID   WP_219644881.1    Uniprot ID   A0AAE4KQW6
Organism   Enterococcus gallinarum strain EG81     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2878070..2889377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HED61_RS14045 - 2878313..2878570 (-) 258 WP_311809712.1 PTS glucose transporter subunit IIA -
  HED61_RS14050 (HED61_14000) - 2878548..2880185 (-) 1638 WP_234981395.1 PTS transporter subunit EIIC -
  HED61_RS14055 (HED61_14005) - 2880310..2881131 (+) 822 WP_103300988.1 MurR/RpiR family transcriptional regulator -
  HED61_RS14060 (HED61_14010) - 2881414..2882262 (-) 849 WP_081131540.1 LEM-3-like GIY-YIG domain-containing protein -
  HED61_RS14065 (HED61_14015) rlmH 2882311..2882790 (-) 480 WP_219644882.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HED61_RS14070 (HED61_14020) htrA 2883070..2884377 (+) 1308 WP_219644881.1 S1C family serine protease Regulator
  HED61_RS14075 (HED61_14025) ytpR 2884432..2885043 (-) 612 WP_003125829.1 YtpR family tRNA-binding protein -
  HED61_RS14080 (HED61_14030) - 2885255..2885710 (-) 456 WP_005470736.1 universal stress protein -
  HED61_RS14085 (HED61_14035) - 2885729..2886043 (-) 315 WP_003125825.1 thioredoxin family protein -
  HED61_RS14090 (HED61_14040) pepA 2886261..2887337 (-) 1077 WP_003125824.1 glutamyl aminopeptidase -
  HED61_RS14095 (HED61_14045) - 2887531..2887875 (+) 345 WP_003125823.1 PepSY domain-containing protein -
  HED61_RS14100 (HED61_14050) - 2887993..2889036 (-) 1044 WP_219644879.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 44793.62 Da        Isoelectric Point: 4.3788

>NTDB_id=435014 HED61_RS14070 WP_219644881.1 2883070..2884377(+) (htrA) [Enterococcus gallinarum strain EG81]
MVRKNVTPGRKPSSGLLKKLGIGILGGVVGGLLTFGGLYLAMGSSLTSPGTTATSGVQDNNGQTKVSNVKYDVNSDVTKA
VEKVQGAVVSIINLQQNNANGLEGLFGSGQQGGQGSGAENSGDDSSLEASSEGSGVIYKVDGDKAYIVTNNHVVEGQDGL
EVVLSDGTKVKAELVGTDAYTDLAVLRISSDKVDTVASFGDSDSLKVGEPAIAIGSPLGSSFANSVTQGIVSSLNRQVTN
QNESGEAVSINAIQTDAAINPGNSGGPLINVEGQVIGINSSKIASTSESTSSVSVEGMGFAIPSNDVVDIINQLEKDGKV
VRPALGIRTINLSSITSQQQEQILKVPSSVTDGVVVYSVNNATPAEQAGLKQYDVITKIDDTDISTTTDLQSALYKHKVG
DTITVTFYRGKEEKTAKVVLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=435014 HED61_RS14070 WP_219644881.1 2883070..2884377(+) (htrA) [Enterococcus gallinarum strain EG81]
ATGGTACGAAAAAATGTGACACCAGGAAGAAAACCTTCTTCCGGTTTATTAAAAAAATTAGGTATTGGCATTCTTGGCGG
AGTAGTTGGTGGTTTGTTGACCTTCGGCGGACTTTATCTGGCGATGGGCTCTTCTTTGACTTCACCTGGAACGACCGCAA
CCAGCGGTGTTCAAGATAACAATGGACAGACGAAAGTCTCCAATGTTAAATATGACGTCAACAGCGATGTAACAAAAGCA
GTCGAAAAAGTGCAAGGAGCAGTCGTTTCGATCATCAACTTGCAACAAAATAATGCGAATGGCCTCGAAGGGTTATTTGG
CTCTGGTCAGCAAGGTGGTCAAGGATCAGGGGCTGAGAATTCAGGCGATGACAGTTCACTAGAAGCTTCTTCTGAAGGAA
GTGGCGTGATTTATAAAGTAGATGGTGACAAAGCGTATATCGTTACGAATAACCACGTAGTAGAAGGACAAGATGGTTTG
GAAGTCGTTCTCTCTGATGGCACAAAAGTCAAAGCTGAATTAGTCGGAACAGACGCTTACACTGACCTTGCTGTTTTACG
CATCTCTTCTGATAAAGTAGACACGGTTGCTTCTTTCGGCGATTCTGATTCACTAAAAGTTGGCGAACCAGCAATTGCGA
TTGGTTCTCCATTAGGATCTAGCTTTGCAAATTCTGTAACACAAGGGATTGTTTCTTCTCTGAACCGTCAAGTAACGAAC
CAAAATGAATCTGGTGAAGCAGTCAGCATCAATGCGATTCAAACAGATGCAGCGATCAACCCAGGAAACTCTGGTGGTCC
ACTGATCAACGTTGAAGGACAAGTGATCGGAATCAACTCTAGCAAGATCGCTAGCACTTCTGAATCAACATCAAGTGTCA
GCGTAGAAGGAATGGGCTTCGCGATCCCAAGTAACGACGTTGTCGATATTATCAATCAATTAGAAAAAGACGGCAAAGTT
GTTCGTCCAGCATTGGGTATTCGAACAATCAACTTAAGCTCAATCACTTCGCAACAACAAGAACAAATCTTGAAAGTACC
ATCTTCTGTCACTGACGGAGTAGTCGTATACTCAGTAAATAACGCGACACCAGCTGAACAAGCAGGATTGAAACAATACG
ATGTCATCACGAAAATCGATGATACAGACATCAGCACAACCACAGATCTACAATCTGCACTGTACAAGCACAAAGTCGGT
GATACGATCACAGTGACGTTCTACCGCGGCAAAGAAGAAAAAACAGCCAAAGTCGTTCTATCTGTAGATACTTCGATCAA
TGAACAATCGACTGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(290-421)

PDZ domain (PDZ_2)

(323-419)

Trypsin-like peptidase domain (Trypsin_2)

(133-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

55.528

91.494

0.508
  htrA Streptococcus gordonii str. Challis substr. CH1

50.827

97.241

0.494
  htrA Streptococcus mitis NCTC 12261

54.331

87.586

0.476
  htrA Streptococcus pneumoniae TIGR4

55.682

80.92

0.451
  htrA Streptococcus pneumoniae Rx1

55.682

80.92

0.451
  htrA Streptococcus pneumoniae D39

55.682

80.92

0.451
  htrA Streptococcus pneumoniae R6

55.682

80.92

0.451