Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   HCJ88_RS10725 Genome accession   NZ_CP050500
Coordinates   2190935..2193127 (-) Length   730 a.a.
NCBI ID   WP_119182947.1    Uniprot ID   -
Organism   Lacticaseibacillus paracasei strain NFFJ04     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2185935..2198127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCJ88_RS10700 (HCJ88_10890) - 2187582..2187893 (-) 312 WP_003580849.1 hypothetical protein -
  HCJ88_RS10705 (HCJ88_10895) - 2187966..2188316 (-) 351 WP_003567340.1 hypothetical protein -
  HCJ88_RS10710 (HCJ88_10900) - 2188490..2189242 (-) 753 Protein_2103 HlyD family efflux transporter periplasmic adaptor subunit -
  HCJ88_RS10715 (HCJ88_10905) - 2189354..2190274 (+) 921 WP_003574021.1 IS30 family transposase -
  HCJ88_RS10720 (HCJ88_10910) - 2190295..2190924 (-) 630 Protein_2105 biotin/lipoyl-binding protein -
  HCJ88_RS10725 (HCJ88_10915) comA 2190935..2193127 (-) 2193 WP_119182947.1 peptide cleavage/export ABC transporter Regulator
  HCJ88_RS10730 (HCJ88_10920) - 2193593..2193730 (-) 138 WP_003571414.1 hypothetical protein -
  HCJ88_RS10735 (HCJ88_10925) - 2194085..2195005 (-) 921 WP_003574021.1 IS30 family transposase -
  HCJ88_RS10740 (HCJ88_10930) - 2195104..2195526 (+) 423 Protein_2109 histidine kinase -
  HCJ88_RS10745 (HCJ88_10935) - 2195638..2196558 (+) 921 WP_003574021.1 IS30 family transposase -
  HCJ88_RS10750 (HCJ88_10940) - 2196579..2197328 (+) 750 Protein_2111 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 730 a.a.        Molecular weight: 81342.56 Da        Isoelectric Point: 7.0227

>NTDB_id=433420 HCJ88_RS10725 WP_119182947.1 2190935..2193127(-) (comA) [Lacticaseibacillus paracasei strain NFFJ04]
MIKYNLKLGQTQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide


Download         Length: 2193 bp        

>NTDB_id=433420 HCJ88_RS10725 WP_119182947.1 2190935..2193127(-) (comA) [Lacticaseibacillus paracasei strain NFFJ04]
ATGATCAAATACAACCTAAAGCTTGGCCAAACACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTTTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGAATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGCCTCATCCTCGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAAATTGTGTCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCTATTATCGAGGACTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAGAATGCCAAATACACCATTGTCGGCATGAGCGGATCAGGAAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGTGTTCCCATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(510-662)

Peptidase C39 family (Peptidase_C39)

(16-152)

ABC transporter transmembrane region (ABC_membrane)

(180-448)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.914

98.356

0.579
  comA Streptococcus pneumoniae Rx1

58.357

98.356

0.574
  comA Streptococcus pneumoniae D39

58.357

98.356

0.574
  comA Streptococcus pneumoniae R6

58.357

98.356

0.574
  comA Streptococcus mitis SK321

58.217

98.356

0.573
  comA Streptococcus pneumoniae TIGR4

57.939

98.356

0.57
  comA Streptococcus gordonii str. Challis substr. CH1

57.103

98.356

0.562
  comA/nlmT Streptococcus mutans UA159

54.986

98.904

0.544