Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   EGM182_RS05550 Genome accession   NZ_CP050490
Coordinates   1017483..1018787 (-) Length   434 a.a.
NCBI ID   WP_015509239.1    Uniprot ID   A0A200IEL7
Organism   Enterococcus casseliflavus strain EGM182     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012483..1023787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGM182_RS05520 (EGM182_05590) - 1012485..1013519 (+) 1035 WP_060791767.1 hypothetical protein -
  EGM182_RS05525 (EGM182_05595) - 1013580..1013924 (-) 345 WP_005225425.1 peptidase -
  EGM182_RS05530 (EGM182_05600) pepA 1014218..1015294 (+) 1077 WP_060791847.1 glutamyl aminopeptidase -
  EGM182_RS05535 (EGM182_05605) - 1015428..1015748 (+) 321 WP_034857755.1 thioredoxin family protein -
  EGM182_RS05540 (EGM182_05610) - 1015761..1016222 (+) 462 WP_005225429.1 universal stress protein -
  EGM182_RS05545 (EGM182_05615) ytpR 1016799..1017413 (+) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  EGM182_RS05550 (EGM182_05620) htrA 1017483..1018787 (-) 1305 WP_015509239.1 S1C family serine protease Regulator
  EGM182_RS05555 (EGM182_05625) rlmH 1019161..1019640 (+) 480 WP_060791768.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EGM182_RS05560 (EGM182_05630) - 1019684..1020544 (+) 861 WP_118214781.1 LEM-3-like GIY-YIG domain-containing protein -
  EGM182_RS05565 (EGM182_05635) truA 1020731..1021468 (+) 738 WP_192415863.1 tRNA pseudouridine(38-40) synthase TruA -
  EGM182_RS05570 (EGM182_05640) map 1021511..1022269 (+) 759 WP_192415865.1 type I methionyl aminopeptidase -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44863.37 Da        Isoelectric Point: 4.0412

>NTDB_id=433285 EGM182_RS05550 WP_015509239.1 1017483..1018787(-) (htrA) [Enterococcus casseliflavus strain EGM182]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVKTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=433285 EGM182_RS05550 WP_015509239.1 1017483..1018787(-) (htrA) [Enterococcus casseliflavus strain EGM182]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGCGGACAAAGTGAAGGCGATAGCCAAAGCGATGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GGGTCATCTACAAAATCGATGGCGACGATGCCTATGTTGTAACCAACAACCACGTCGTAGAAGGTCAAGACGGTTTAGAA
GTTGTTTTAGCAGACGGTACGAAAGTCAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTGGCTGTATTGAAAAT
CTCTTCAGAGCATGTGAAGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCAATCGCAATCG
GCTCTCCTCTCGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGTCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TGGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTT
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCTGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGACACAGAAGTCAGCACAACAACGGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A200IEL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.171

91.475

0.514
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.432

82.719

0.459
  htrA Streptococcus pneumoniae TIGR4

57.018

78.802

0.449
  htrA Streptococcus pneumoniae Rx1

57.018

78.802

0.449
  htrA Streptococcus pneumoniae D39

57.018

78.802

0.449
  htrA Streptococcus pneumoniae R6

57.018

78.802

0.449