Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   HB752_RS09160 Genome accession   NZ_CP050271
Coordinates   1878295..1878873 (-) Length   192 a.a.
NCBI ID   WP_019804608.1    Uniprot ID   -
Organism   Streptococcus mutans strain S1     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1862940..1897340 1878295..1878873 within 0


Gene organization within MGE regions


Location: 1862940..1897340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB752_RS09100 (HB752_09100) - 1862940..1864319 (-) 1380 WP_002283797.1 Eco57I restriction-modification methylase domain-containing protein -
  HB752_RS09105 (HB752_09105) - 1864395..1865270 (-) 876 WP_049473435.1 Abi family protein -
  HB752_RS10385 - 1865422..1865592 (-) 171 Protein_1773 type II toxin-antitoxin system RelE/ParE family toxin -
  HB752_RS09110 (HB752_09110) - 1865765..1866274 (-) 510 WP_002277793.1 HXXEE domain-containing protein -
  HB752_RS09115 (HB752_09115) - 1866442..1866984 (+) 543 WP_002274465.1 TetR/AcrR family transcriptional regulator -
  HB752_RS09120 (HB752_09120) purH 1867167..1868717 (-) 1551 WP_049473434.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  HB752_RS09125 (HB752_09125) - 1869053..1869952 (-) 900 WP_002264110.1 exonuclease domain-containing protein -
  HB752_RS09130 (HB752_09130) purN 1869998..1870543 (-) 546 WP_049473433.1 phosphoribosylglycinamide formyltransferase -
  HB752_RS09135 (HB752_09135) purM 1870543..1871565 (-) 1023 WP_049473432.1 phosphoribosylformylglycinamidine cyclo-ligase -
  HB752_RS09140 (HB752_09140) purF 1871624..1873063 (-) 1440 WP_002263130.1 amidophosphoribosyltransferase -
  HB752_RS09145 (HB752_09145) - 1873089..1873709 (-) 621 WP_002267556.1 DNA alkylation repair protein -
  HB752_RS09150 (HB752_09150) - 1873731..1877456 (-) 3726 WP_019804609.1 phosphoribosylformylglycinamidine synthase -
  HB752_RS09155 (HB752_09155) purC 1877466..1878173 (-) 708 WP_002269789.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  HB752_RS09160 (HB752_09160) comA 1878295..1878873 (-) 579 WP_019804608.1 ATP-binding cassette domain-containing protein Regulator
  HB752_RS09165 (HB752_09165) - 1879101..1879349 (-) 249 WP_019804607.1 acyl carrier protein -
  HB752_RS09170 (HB752_09170) plsX 1879351..1880349 (-) 999 WP_002269788.1 phosphate acyltransferase PlsX -
  HB752_RS09175 (HB752_09175) recO 1880557..1881312 (-) 756 WP_002269787.1 DNA repair protein RecO -
  HB752_RS09180 (HB752_09180) - 1881302..1882477 (-) 1176 WP_002264118.1 pyridoxal phosphate-dependent aminotransferase -
  HB752_RS09185 (HB752_09185) - 1882566..1883534 (-) 969 WP_002263139.1 ribose-phosphate diphosphokinase -
  HB752_RS09190 (HB752_09190) - 1883650..1884942 (-) 1293 WP_019804606.1 CHAP domain-containing protein -
  HB752_RS09195 (HB752_09195) mreD 1885052..1885558 (-) 507 WP_002263141.1 rod shape-determining protein MreD -
  HB752_RS09200 (HB752_09200) mreC 1885560..1886378 (-) 819 WP_002263142.1 rod shape-determining protein MreC -
  HB752_RS09310 (HB752_09310) - 1893468..1894883 (-) 1416 WP_002275393.1 amino acid permease -
  HB752_RS09315 (HB752_09315) ftsH 1895370..1897340 (-) 1971 WP_002264625.1 ATP-dependent zinc metalloprotease FtsH -

Sequence

Protein


Download         Length: 192 a.a.        Molecular weight: 21287.26 Da        Isoelectric Point: 4.8856

>NTDB_id=431147 HB752_RS09160 WP_019804608.1 1878295..1878873(-) (comA) [Streptococcus mutans strain S1]
MGKSGSGKTTLAKILAGYYTVSSGDSFLDGEKINYSQLRQLVTYVPQQSYVFTGTILDNLLLGAEEEVTDDRLMEVCSIA
EILDDIKAMPLGFQTQISEDGGLSGGQKQRLAIARALLTRQPVLIFDEATSGLDRDTEEKVIANLSKLNRTIIFIAHRSV
SYYADRIVEIDSGEKIKDRINHRPFSFLMTTL

Nucleotide


Download         Length: 579 bp        

>NTDB_id=431147 HB752_RS09160 WP_019804608.1 1878295..1878873(-) (comA) [Streptococcus mutans strain S1]
ATGGGGAAAAGTGGTTCTGGAAAGACAACTTTGGCAAAAATTCTTGCAGGCTATTATACTGTTAGTAGCGGTGACTCTTT
CTTAGATGGAGAAAAGATAAATTATTCCCAGCTGCGCCAATTAGTAACTTATGTGCCACAGCAGTCTTATGTTTTTACAG
GAACAATCTTAGATAATCTACTTCTTGGTGCTGAAGAGGAAGTAACGGATGATCGCTTAATGGAAGTTTGTTCAATTGCT
GAAATTTTAGACGATATCAAGGCAATGCCTTTAGGTTTTCAAACACAGATTTCAGAAGACGGCGGTTTATCTGGTGGTCA
AAAACAGCGTTTAGCTATTGCACGTGCTCTCTTAACCAGACAGCCTGTGTTGATTTTTGATGAGGCAACTAGTGGTTTAG
ATCGTGATACCGAAGAAAAAGTTATTGCCAATTTATCTAAATTGAATCGCACGATTATTTTTATTGCTCACCGCAGTGTT
TCTTATTATGCTGATCGAATTGTTGAGATTGACTCTGGAGAGAAAATTAAGGACAGAATAAATCATCGTCCTTTCTCATT
TTTGATGACGACTCTTTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(1-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

51.337

97.396

0.5
  comA Streptococcus gordonii str. Challis substr. CH1

51.648

94.792

0.49
  comA/nlmT Streptococcus mutans UA159

49.468

97.917

0.484
  comA Streptococcus pneumoniae D39

49.727

95.313

0.474
  comA Streptococcus pneumoniae Rx1

49.727

95.313

0.474
  comA Streptococcus pneumoniae R6

49.727

95.313

0.474
  comA Streptococcus mitis SK321

48.634

95.313

0.464
  comA Streptococcus pneumoniae TIGR4

48.634

95.313

0.464